AGPAT5 and CYB561A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AGPAT5	CYB561A3
Description		1-acylglycerol-3-phosphate O-acyltransferase 5	cytochrome b561 family member A3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleolus Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane	Nucleolus Lysosome Lysosomal Membrane Endosome Membrane Late Endosome Membrane
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Ascorbate Ferrireductase Activity
	Biological Process	Hematopoietic Progenitor Cell Differentiation Lipid Metabolic Process Acylglycerol Metabolic Process Phosphatidic Acid Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Phosphatidylinositol Acyl-chain Remodeling	Intracellular Iron Ion Homeostasis Transmembrane Transport
Pathways		Synthesis of PA
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) HDL cholesterol ( 30275531) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		6 interacting genes: CREB3L1 CYB561A3 PSCA SCN3B TMX2 UBQLN1	23 interacting genes: AGPAT5 AOC1 AQP6 CD40 CD79A CLDN5 CLDN7 CREB3L3 EHHADH FFAR2 GPR101 GPR152 GPR37L1 GPX8 HERPUD2 KLRC1 LAPTM4B PVR RNF185 RNF5 SHISAL1 TM4SF18 TMEM31
Entrez ID		55326	220002
HPRD ID		12438	11316
Ensembl ID		ENSG00000155189	ENSG00000162144
Uniprot IDs		A0A024R640 Q9NUQ2	F5H1Q2 Q8NBI2
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Positive Regulation Of Immune Response Positive Regulation Of Immune Effector Process Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Apicolateral Plasma Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Acute Inflammatory Response Positive Regulation Of Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Protein Alpha-1,2-demannosylation Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Mannose Trimming Endoplasmic Reticulum Quality Control Compartment Protein Deglycosylation Bicellular Tight Junction Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Diamine Oxidase Activity Putrescine Oxidase Activity Histamine Oxidase Activity Nitrate Transmembrane Transporter Activity Regulation Of Immune Response Immune Response-activating Signaling Pathway Positive Regulation Of Natural Killer Cell Mediated Immunity Inhibitory MHC Class Ib Receptor Activity B Cell Proliferation G Protein-coupled Receptor Activity Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Immune System Process Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Activation Of Immune Response Bicellular Tight Junction Assembly Tight Junction Organization Tight Junction Assembly Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds Innate Immune Response-activating Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Regulation Of Innate Immune Response Activation Of Innate Immune Response Regulation Of Acute Inflammatory Response HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Receptor Complex Regulation Of T Cell Mediated Cytotoxicity
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