BOLA2 and ZNF511

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BOLA2	ZNF511
Description		bolA family member 2	zinc finger protein 511
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Iron-sulfur Cluster Assembly Complex	Nucleus
	Molecular Function	Protein Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation	Regulation Of DNA-templated Transcription
Pathways		Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Nonunion in individuals with fractures ( 30680360)
Interacting Genes		32 interacting genes: ADAMTSL4 ANKRD55 BIRC2 BIRC7 C10orf55 C1orf94 CCDC138 CGGBP1 GLRX3 HDX ID3 IHO1 IL16 MBD3L1 MEOX2 MOBP NTAQ1 RAB4B RGS17 SLITRK5 TK1 TXNRD3 XIAP ZFP90 ZNF177 ZNF511 ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF76 ZNF774	14 interacting genes: BOLA2 BOLA2B CFAP206 CLCNKA ENKD1 HSF2BP ISL1 KAT5 LHX2 LMO1 MAD2L2 NTAQ1 SCNM1 SMARCD1
Entrez ID		552900	118472
HPRD ID		18842	15812
Ensembl ID		ENSG00000183336	ENSG00000198546
Uniprot IDs		A0A499FJE1 Q9H3K6	Q8NB15
PDB IDs
Enriched GO Terms of Interacting Partners?		Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Protein Polyubiquitination Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Polyubiquitination Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Metal Ion Binding Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of Transcription By RNA Polymerase II Pigment Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Natural Killer Cell Apoptotic Process	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Negative Regulation Of Cell Differentiation Positive Regulation Of Double-strand Break Repair Regulation Of Sister Chromatid Segregation Regulation Of Double-strand Break Repair Positive Regulation Of DNA Repair Regulation Of Chromosome Segregation Negative Regulation Of Double-strand Break Repair Via Homologous Recombination 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Negative Regulation Of Developmental Process Chromatin Binding Regulation Of Lymphocyte Activation Positive Regulation Of Myoblast Differentiation Regulation Of DNA Repair Negative Regulation Of DNA Repair Double-strand Break Repair Negative Regulation Of DNA Recombination DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Double-strand Break Repair Establishment Of Mitotic Spindle Localization Histone H2AK5 Acetyltransferase Activity Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation Protein-N-terminal Glutamine Amidohydrolase Activity A Axonemal Microtubule Cell Redox Homeostasis Regulation Of Chromosome Organization Establishment Of Spindle Localization Spindle Localization Chromatin Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of DNA Metabolic Process Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Transcription Coactivator Activity Regulation Of Cell Activation Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Protein-N-terminal Asparagine Amidohydrolase Activity Regulation Of Myoblast Differentiation Positive Regulation Of DNA Recombination Positive Regulation Of RNA Metabolic Process Regulation Of Double-strand Break Repair Via Homologous Recombination Visceral Motor Neuron Differentiation Positive Regulation Of Macrophage Colony-stimulating Factor Production Positive Regulation Of Granulocyte Colony-stimulating Factor Production
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