BOLA2 and SLITRK5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BOLA2	SLITRK5
Description		bolA family member 2	SLIT and NTRK like family member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Iron-sulfur Cluster Assembly Complex	Plasma Membrane Membrane Receptor Complex Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding
	Biological Process	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation	Chemical Synaptic Transmission Axonogenesis Grooming Behavior Response To Xenobiotic Stimulus Striatum Development Adult Behavior Skin Development Dendrite Morphogenesis Positive Regulation Of Synapse Assembly Circulatory System Development Synaptic Membrane Adhesion Regulation Of Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission
Pathways		Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Receptor-type tyrosine-protein phosphatases RAC2 GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS			Male sexual orientation ( 29217827) Metabolite levels ( 23823483) Mild influenza (H1N1) infection ( 26379185)
Interacting Genes		32 interacting genes: ADAMTSL4 ANKRD55 BIRC2 BIRC7 C10orf55 C1orf94 CCDC138 CGGBP1 GLRX3 HDX ID3 IHO1 IL16 MBD3L1 MEOX2 MOBP NTAQ1 RAB4B RGS17 SLITRK5 TK1 TXNRD3 XIAP ZFP90 ZNF177 ZNF511 ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF76 ZNF774	3 interacting genes: BOLA2 BOLA2B CLCNKA
Entrez ID		552900	26050
HPRD ID		18842	18065
Ensembl ID		ENSG00000183336	ENSG00000165300
Uniprot IDs		A0A499FJE1 Q9H3K6	O94991
PDB IDs
Enriched GO Terms of Interacting Partners?		Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Protein Polyubiquitination Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Polyubiquitination Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Metal Ion Binding Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of Transcription By RNA Polymerase II Pigment Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Natural Killer Cell Apoptotic Process	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Cell Redox Homeostasis Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Protein Maturation Transepithelial Chloride Transport Voltage-gated Chloride Channel Activity Inorganic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Intracellular Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Intracellular Chemical Homeostasis Chloride Transmembrane Transporter Activity Cellular Homeostasis Transepithelial Transport Renal Absorption Chemical Homeostasis Chloride Channel Complex Chloride Channel Activity Homeostatic Process Chloride Transmembrane Transport Chloride Transport Inorganic Anion Transmembrane Transport Renal System Process Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport
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