TMEM143 and SFT2D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM143	SFT2D2
Description		transmembrane protein 143	SFT2 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane	Cytoplasm Endomembrane System Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Protein Transport Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease ( 30636644) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		14 interacting genes: ABHD16A AQP6 CSGALNACT2 DGAT2L6 DHRSX LIME1 LSMEM2 NAT8 ORMDL1 REEP6 SFT2D2 SLC10A6 TMEM120B YIPF2	29 interacting genes: AQP6 ATP5PF BNIP2 CREB3 ELOVL4 GPR152 HIBADH HSD17B11 HSD17B13 IFNGR2 INPP5K LMNA MOB2 NDRG4 PBX3 PLIN2 PLIN3 REEP2 REEP4 SLC10A1 SLC10A6 SLC30A8 STOM TAS2R5 TCP11X2 TIMM44 TMEM143 TMEM14B TMEM51
Entrez ID		55260	375035
HPRD ID		08556	14192
Ensembl ID		ENSG00000161558	ENSG00000213064
Uniprot IDs		B4DMT0 B4DPF8 Q96AN5	O95562
PDB IDs
Enriched GO Terms of Interacting Partners?		Nitrate Transmembrane Transporter Activity Membrane Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus L-cysteine-S-conjugate N-acetyltransferase Activity Dolichal Reductase (NADPH) Activity Polyprenol Dehydrogenase (NAD+) Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Intracellular Transport Of Viral Protein In Host Cell Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Peptidyl-lysine N6-acetylation Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Acylglycerol Acyl-chain Remodeling Phospholipid Metabolic Process Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoacylglycerol Catabolic Process B Cell Receptor Complex Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Bile Acid:sodium Symporter Activity Diacylglycerol O-acyltransferase Activity	Positive Regulation Of Triglyceride Storage Steroid Dehydrogenase Activity Lipid Droplet Bile Acid:sodium Symporter Activity Lipid Droplet Disassembly Endoplasmic Reticulum Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Membrane Positive Regulation Of Lipid Storage Bile Acid And Bile Salt Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Nuclear Envelope Organization
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