TMEM143 and TMEM120B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM143	TMEM120B
Description		transmembrane protein 143	transmembrane protein 120B
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Membrane	Nucleus Nuclear Inner Membrane Membrane
	Molecular Function	Molecular_function Protein Binding	Monoatomic Ion Channel Activity Protein Binding
	Biological Process	Biological_process	Fat Cell Differentiation Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS			HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 24026423 27863252 32888494) Mean reticulocyte volume ( 32888494) Molybdenum levels ( 26025379) Neutrophil count ( 32888494) Platelet count ( 27863252 32888494) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: ABHD16A AQP6 CSGALNACT2 DGAT2L6 DHRSX LIME1 LSMEM2 NAT8 ORMDL1 REEP6 SFT2D2 SLC10A6 TMEM120B YIPF2	59 interacting genes: ALOX5AP ANKS6 APOA5 AQP6 AQP8 ARL13B BNIP3L CCNDBP1 CD74 COMT CPLX4 CREB3L1 EBP ERGIC3 FCER1G FFAR2 FKBP7 GAD2 GJB1 GORAB GPR152 GPRC5D GPX8 HSD17B11 HSD17B13 IFNGR2 IL7R JAGN1 JPH1 KCNJ6 LMNA LRRTM2 MGST3 MRPS18B MUC1 NCAPH2 REEP2 REEP4 RETREG3 RNF19B RNF5 SCN3B SH3GL3 SLC10A1 SLC10A6 SLC17A8 SLC18A1 SLC1A3 SLC35H1 STOM STX2 TLCD4 TMEM139 TMEM143 TMEM14B TMEM80 TMPRSS2 TMX2 ZDHHC15
Entrez ID		55260	144404
HPRD ID		08556	19119
Ensembl ID		ENSG00000161558	ENSG00000188735
Uniprot IDs		B4DMT0 B4DPF8 Q96AN5	A0PK00
PDB IDs			7F73
Enriched GO Terms of Interacting Partners?		Nitrate Transmembrane Transporter Activity Membrane Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus L-cysteine-S-conjugate N-acetyltransferase Activity Dolichal Reductase (NADPH) Activity Polyprenol Dehydrogenase (NAD+) Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Intracellular Transport Of Viral Protein In Host Cell Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Peptidyl-lysine N6-acetylation Acylglycerol Metabolic Process Neutral Lipid Metabolic Process Glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Acylglycerol Acyl-chain Remodeling Phospholipid Metabolic Process Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoacylglycerol Catabolic Process B Cell Receptor Complex Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Bile Acid:sodium Symporter Activity Diacylglycerol O-acyltransferase Activity	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Organic Hydroxy Compound Transport Steroid Dehydrogenase Activity Glutathione Peroxidase Activity Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Leukotriene-C4 Synthase Activity Bile Acid:sodium Symporter Activity Transmembrane Transport Monoamine Transport Leukocyte Mediated Immunity Gamma-aminobutyric Acid Biosynthetic Process Prostanoid Metabolic Process Neurotransmitter Loading Into Synaptic Vesicle Regulation Of Transport Norepinephrine Transport Gamma-aminobutyric Acid Metabolic Process Icosanoid Metabolic Process Ammonium Channel Activity Neurotransmitter Transport Symporter Activity Icosanoid Biosynthetic Process Ammonium Transmembrane Transport Cellular Response To Cocaine Cellular Detoxification Negative Regulation Of Peptide Secretion Amine Transport Cytokine Receptor Activity Serotonin Transport L-glutamate Transmembrane Transporter Activity Lymphocyte Mediated Immunity Non-motile Cilium Assembly Nuclear Envelope Water Channel Activity Negative Regulation Of Leukocyte Apoptotic Process
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