VRTN and RAB3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VRTN	RAB3C
Description		vertebrae development associated	RAB3C, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Sequence-specific DNA Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		FEV1 ( 30804560) Lung function (FVC) ( 30804560) Refractive error ( 32231278)	Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		10 interacting genes: C9orf72 CTBP2 EIF4A3 FAM90A1 POLR3C RAB2B RAB3A RAB3B RAB3C RAB3D	7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN
Entrez ID		55237	115827
HPRD ID		16593	06704
Ensembl ID		ENSG00000133980	ENSG00000152932
Uniprot IDs		Q9H8Y1	Q96E17
PDB IDs			6Y7G
Enriched GO Terms of Interacting Partners?		Myosin V Binding Regulation Of Exocytosis GTP-dependent Protein Binding Regulation Of Vesicle-mediated Transport Regulation Of Secretion By Cell Regulation Of Secretion GTPase Activity Synaptic Vesicle GTP Binding Exocytosis Positive Regulation Of Exocytosis Vesicle-mediated Transport Endosome Regulation Of Synaptic Vesicle Cycle Secretion By Cell Regulation Of Transport Hydrolase Activity Vesicle Nucleotide Binding Secretion Protein Transport Postsynapse Positive Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Positive Regulation Of Secretion By Cell Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Positive Regulation Of Secretion Positive Regulation Of Transport Sensory Perception Of Touch Positive Regulation Of Type I Interferon Production Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Regulation Of Dense Core Granule Exocytosis Acrosomal Vesicle Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Secretory Granule Zymogen Granule Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Intracellular Protein Localization Clathrin-sculpted Glutamate Transport Vesicle Membrane Regulation Of Regulated Secretory Pathway Selenocysteine Insertion Sequence Binding Regulation Of Translation At Postsynapse Regulation Of Type I Interferon Production Synaptic Vesicle Membrane Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Acrosomal Vesicle Exocytosis
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