FAM86C1P and KYNU

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM86C1P	KYNU
Description		family with sequence similarity 86, member C	kynureninase
Image		No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity	Protein Binding Hydrolase Activity Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity
	Biological Process	Methylation	L-tryptophan Catabolic Process Nucleoside Phosphate Metabolic Process NAD+ Biosynthetic Process Pyridine Nucleotide Biosynthetic Process L-tryptophan Catabolic Process To Kynurenine Quinolinate Biosynthetic Process Response To Type II Interferon 'de Novo' NAD+ Biosynthetic Process From L-tryptophan Response To Vitamin B6 Anthranilate Metabolic Process Purine-containing Compound Metabolic Process L-kynurenine Catabolic Process
Pathways			Tryptophan catabolism
Drugs			Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Asthma and eczema ( 34155719) Blood protein levels ( 30072576) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		22 interacting genes: AIRIM ANKS1A BCAS2 CDKN2D CDR2L COL8A1 CRACR2A CSNK2B CTTNBP2 DOK6 GPSM3 HNRNPF KRT26 KYNU MAGED4B PCSK5 POU4F2 SAT1 SMYD1 SPG21 TRAF1 VENTX	9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3
Entrez ID		55199	8942
HPRD ID		13337	08940
Ensembl ID		ENSG00000158483	ENSG00000115919
Uniprot IDs			Q16719 Q53SX6
PDB IDs			2HZP 3E9K 7S3V
Enriched GO Terms of Interacting Partners?
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