FAM86C1P and CTTNBP2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		FAM86C1P	CTTNBP2
Name		family with sequence similarity 86, member C	cortactin binding protein 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	Cytoplasm Cell Cortex Synaptic Vesicle Cell Projection Dendritic Spine Synapse FAR/SIN/STRIPAK Complex Postsynaptic Actin Cytoskeleton Glutamatergic Synapse
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity	Protein Binding SH3 Domain Binding
	Biological Process	Methylation	Regulation Of Synapse Organization Regulation Of Modification Of Postsynaptic Actin Cytoskeleton
GWAS		No GWAS studies recorded	Brain morphology (MOSTest) ( 32665545 ) General factor of neuroticism ( 30867560 ) Glaucoma ( 30054594 31959993 ) Glaucoma (primary open-angle) ( 33627673 29891935 ) Idiopathic osteonecrosis of the femoral head ( 28000841 ) Intraocular pressure ( 29617998 29785010 30054594 31959993 ) Myocardial infarction ( 33532862 ) Positive urgency ( 30718321 ) Response to methotrexate in juvenile idiopathic arthritis ( 24709693 ) Smoking initiation ( 30617275 33082346 ) Smoking initiation (ever regular vs never regular) ( 30679032 ) Smoking status (current vs never) ( 33082346 ) Smoking status (ever vs never smokers) ( 30643258 ) Sociability score ( 34054130 ) Subcortical volume (MOSTest) ( 32665545 ) Triglyceride levels ( 30108155 ) Type 2 diabetes ( 30297969 30054458 ) Waist-to-hip ratio adjusted for BMI ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 ) Worry too long after an embarrassing experience ( 34054130 )
Novel Interactors		None recorded	1 novel interactors: IMMP2L
Interacting Genes		22 interacting genes: AIRIM ANKS1A BCAS2 CDKN2D CDR2L COL8A1 CRACR2A CSNK2B CTTNBP2 DOK6 GPSM3 HNRNPF KRT26 KYNU MAGED4B PCSK5 POU4F2 SAT1 SMYD1 SPG21 TRAF1 VENTX	10 interacting genes: APPL1 BMAL2 CTTN FAM86C1P HSF2BP INCA1 KRT14 MAGEA11 MEI4 PKNOX2
Entrez ID		55199	83992
HPRD ID		13337	09890
Ensembl ID		ENSG00000158483	ENSG00000077063
Uniprot IDs		Not available	Q20BG9 Q8WZ74
PDB IDs		Not available	Not available