KYNU and CT55

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KYNU	CT55
Description		kynureninase	cancer/testis antigen 55
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol	Acrosomal Vesicle Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection
	Molecular Function	Protein Binding Hydrolase Activity Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	L-tryptophan Catabolic Process Nucleoside Phosphate Metabolic Process NAD+ Biosynthetic Process Pyridine Nucleotide Biosynthetic Process L-tryptophan Catabolic Process To Kynurenine Quinolinate Biosynthetic Process Response To Type II Interferon 'de Novo' NAD+ Biosynthetic Process From L-tryptophan Response To Vitamin B6 Anthranilate Metabolic Process Purine-containing Compound Metabolic Process L-kynurenine Catabolic Process	Spermatogenesis
Pathways		Tryptophan catabolism
Drugs		Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Asthma and eczema ( 34155719) Blood protein levels ( 30072576) Cataracts ( 34127677) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3	32 interacting genes: AIRIM BFSP2 CABP5 CATSPERT CPNE2 DES EXOC7 FAAP20 GFAP GPRASP3 KIAA0753 KLC3 KLHL42 KYNU LYPLAL1 MBD3 MEMO1 MEOX2 P4HA3 PAX7 PIH1D2 PRPH SAMD11 SHC3 SNF8 SPG21 TFIP11 TLE5 TXLNB VIM ZNF177 ZNF559-ZNF177
Entrez ID		8942	54967
HPRD ID		08940	06534
Ensembl ID		ENSG00000115919	ENSG00000169551
Uniprot IDs		Q16719 Q53SX6	Q8WUE5
PDB IDs		2HZP 3E9K 7S3V
Enriched GO Terms of Interacting Partners?			Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Cytoskeleton Intermediate Filament Intermediate Filament Cytoskeleton Lens Fiber Cell Development Bergmann Glial Cell Differentiation Protein Binding Astrocyte Development
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