ATG16L1 and TMEM59

Number of citations of the paper that reports this interaction (PMID 23376921)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ATG16L1	TMEM59
Gene Name		autophagy related 16-like 1 (S. cerevisiae)	transmembrane protein 59
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Autophagic Vacuole Membrane Autophagic Vacuole Axoneme Pre-autophagosomal Structure Membrane	Golgi Cis Cisterna Golgi Trans Cisterna Golgi Membrane Lysosome Lysosomal Membrane Late Endosome Golgi Medial Cisterna Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Endopeptidase Activity Protein Binding
	Biological Process	Autophagic Vacuole Assembly Protein Transport Negative Stranded Viral RNA Replication Protein Homooligomerization	Proteolysis Autophagy Positive Regulation Of Autophagy Negative Regulation Of Protein Processing Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Protein Glycosylation In Golgi
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 20570966 22936669 22412388 17435756 17554300 21102463 23128233)
Protein-Protein Interactions		6 interactors: APP ATG5 RAB33A RAB33B TMEM59 UBC	1 interactors: ATG16L1
Entrez ID		55054	9528
HPRD ID		16498	12731
Ensembl ID		ENSG00000085978	ENSG00000116209
Uniprot IDs		E7EVC7 Q17RG0 Q53SV2 Q676U5	D3DQ48 Q9BXS4
PDB IDs		4GDK 4GDL
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Autophagic Vacuole Assembly Autophagy Regulation Of Vacuole Organization Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Type I Interferon Production Rab Protein Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Intracellular Transport Negative Regulation Of Constitutive Secretory Pathway Negative Regulation Of Protein Ubiquitination Regulation Of Type I Interferon Production Catabolic Process Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Growth At Neuromuscular Junction Negative Regulation Of Protein Glycosylation In Golgi Notch Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Innate Immune Response Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Metabolic Process Immune System Process Regulation Of Protein Metabolic Process Viral Life Cycle Negative Regulation Of Protein Glycosylation Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Organelle Organization Regulation Of Protein Ubiquitination Negative Regulation Of Cytokine Production Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Cellular Localization Regulation Of Cell Cycle Phase Transition Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cellular Localization Cell Death Death Otolith Development Axon Choice Point Recognition	Negative Stranded Viral RNA Replication Viral Genome Replication Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Viral Life Cycle Cellular Response To Extracellular Stimulus Protein Homooligomerization
Tagcloud ?		1alpha 20a atg12 atg5 atg7 atg9a atgs autophagic autophagy becn1 cfos confirming ctsk decisive deregulation hif hypoxia hypoxic lc3 mirna mmp9 nfatc1 osteoclast p62 prime raw264 shrna traf6 utr	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		1alpha 20a atg12 atg5 atg7 atg9a atgs autophagic autophagy becn1 cfos confirming ctsk decisive deregulation hif hypoxia hypoxic lc3 mirna mmp9 nfatc1 osteoclast p62 prime raw264 shrna traf6 utr	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 ssbp1 stxbp3 syncrip syne2 tangles treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?