ATG16L1

Gene Name		autophagy related 16-like 1 (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Autophagic Vacuole Membrane Autophagic Vacuole Axoneme Pre-autophagosomal Structure Membrane
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Autophagic Vacuole Assembly Protein Transport Negative Stranded Viral RNA Replication Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 18587394 20570966 22936669 22412388 17435756 17554300 21102463 23128233)
Protein-protein Interactions		6 interactors: APP ATG5 RAB33A RAB33B TMEM59 UBC
Entrez ID		55054
HPRD ID		16498
Ensembl ID		ENSG00000085978
Uniprot IDs		E7EVC7 Q17RG0 Q53SV2 Q676U5
PDB IDs		4GDK 4GDL
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Autophagic Vacuole Assembly Autophagy Regulation Of Vacuole Organization Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Type I Interferon Production Rab Protein Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Intracellular Transport Negative Regulation Of Constitutive Secretory Pathway Negative Regulation Of Protein Ubiquitination Regulation Of Type I Interferon Production Catabolic Process Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Growth At Neuromuscular Junction Negative Regulation Of Protein Glycosylation In Golgi Notch Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Innate Immune Response Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Metabolic Process Immune System Process Regulation Of Protein Metabolic Process Viral Life Cycle Negative Regulation Of Protein Glycosylation Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Organelle Organization Regulation Of Protein Ubiquitination Negative Regulation Of Cytokine Production Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Cellular Localization Regulation Of Cell Cycle Phase Transition Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cellular Localization Cell Death Death Otolith Development Axon Choice Point Recognition
Tagcloud ?		1alpha 20a atg12 atg5 atg7 atg9a atgs autophagic autophagy becn1 cfos confirming ctsk decisive deregulation hif hypoxia hypoxic lc3 mirna mmp9 nfatc1 osteoclast p62 prime raw264 shrna traf6 utr