TMEM59

Description		transmembrane protein 59
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Cis Cisterna Golgi Trans Cisterna Golgi Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Golgi Apparatus Golgi Medial Cisterna Plasma Membrane Membrane Late Endosome Membrane Extracellular Exosome
	Molecular Function	Endopeptidase Activity Protein Binding
	Biological Process	Protein Glycosylation Autophagy Positive Regulation Of Autophagy Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		RHOH GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231) Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		2 interacting genes: DYRK1A ERRFI1
Entrez ID		9528
HPRD ID		12731
Ensembl ID		ENSG00000116209
Uniprot IDs		Q5T6Z8 Q5T703 Q9BXS4
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Negative Regulation Of Microtubule Polymerization Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Heterochromatin Formation Regulation Of Neurofibrillary Tangle Assembly Neurofilament Splicing Factor Binding Regulation Of Heterochromatin Formation Histone H3T45 Kinase Activity Negative Regulation Of Protein Autophosphorylation Chondrocyte Proliferation Negative Regulation Of Collagen Biosynthetic Process Skin Morphogenesis Negative Regulation Of Signaling Receptor Activity Oviduct Epithelium Development Lung Vasculature Development Limb Joint Morphogenesis Uterine Epithelium Development Fat Pad Development Progesterone Receptor Signaling Pathway Regulation Of Type B Pancreatic Cell Proliferation Lung Epithelium Development Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Autophosphorylation Response To 1-oleoyl-sn-glycerol 3-phosphate Tau-protein Kinase Activity Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Chromatin Organization Negative Regulation Of Intracellular Signal Transduction Regulation Of Inclusion Body Assembly Negative Regulation Of Peptidyl-tyrosine Phosphorylation Cellular Hyperosmotic Response Response To Platelet-derived Growth Factor Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Uterus Development Bile Acid Biosynthetic Process Regulation Of Protein Tyrosine Kinase Activity Hyperosmotic Response Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of RNA Splicing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Dexamethasone Stimulus System Development Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of ERBB Signaling Pathway Bile Acid Metabolic Process Response To Progesterone
Tagcloud ?