PHIP and STMN4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHIP	STMN4
Gene Name		pleckstrin homology domain interacting protein	stathmin-like 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Axon Growth Cone Neuron Projection
	Molecular Function	Insulin Receptor Binding Protein Binding Lysine-acetylated Histone Binding	Tubulin Binding
	Biological Process	Regulation Of Protein Phosphorylation Protein Import Into Nucleus Cytoskeleton Organization Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Regulation Of Cell Shape Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Cell Morphogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Microtubule Depolymerization Regulation Of Microtubule Polymerization Or Depolymerization Neuron Projection Development Regulation Of Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: IRS1 STMN4 TUBB3	2 interactors: IMMT PHIP
Entrez ID		55023	81551
HPRD ID		10152	18120
Ensembl ID		ENSG00000146247	ENSG00000015592
Uniprot IDs		A7J992 Q8WWQ0	E7EVN3 Q9H169
PDB IDs		3MB3
Enriched GO Terms of Interacting Partners?		Microtubule Depolymerization Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Glucose Import In Response To Insulin Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Phosphatidylinositol 3-kinase Signaling Microtubule-based Process Positive Regulation Of Insulin Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Positive Regulation Of Lipid Catabolic Process Cellular Response To Growth Hormone Stimulus Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Glucose Metabolic Process Neuron Development Regulation Of Glycogen Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Insulin Secretion Protein Kinase B Signaling Response To Growth Hormone Microtubule Polymerization Or Depolymerization Negative Regulation Of Peptide Secretion Positive Regulation Of Mesenchymal Cell Proliferation System Development Positive Regulation Of Glucose Import Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Glucose Transport Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Differentiation JAK-STAT Cascade Cell Projection Organization 'de Novo' Posttranslational Protein Folding Regulation Of Lipid Catabolic Process Regulation Of Lipid Kinase Activity 'de Novo' Protein Folding Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Hormone Secretion Multicellular Organismal Development Regulation Of Glucose Import Anatomical Structure Development Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Stem Cell Proliferation Regulation Of Generation Of Precursor Metabolites And Energy
Tagcloud ?		achievable affordable benzo butanone carcinogenesis carcinogens coexposure cooked endpoints ergosterol holistically intervene legumes meats methylnitrosamino mimosine mushrooms nbp nnk noncytotoxic phenylimidazo physiologically polluted pyrene pyridine pyridyl reinforced sporadically talk
Tagcloud (Difference) ?		achievable affordable benzo butanone carcinogenesis carcinogens coexposure cooked endpoints ergosterol holistically intervene legumes meats methylnitrosamino mimosine mushrooms nbp nnk noncytotoxic phenylimidazo physiologically polluted pyrene pyridine pyridyl reinforced sporadically talk
Tagcloud (Intersection) ?