PHIP

Gene Name		pleckstrin homology domain interacting protein
Image
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Insulin Receptor Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Regulation Of Protein Phosphorylation Protein Import Into Nucleus Cytoskeleton Organization Positive Regulation Of Cell Proliferation Insulin Receptor Signaling Pathway Regulation Of Cell Shape Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Cell Morphogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Growth Negative Regulation Of Apoptotic Process Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: IRS1 STMN4 TUBB3
Entrez ID		55023
HPRD ID		10152
Ensembl ID		ENSG00000146247
Uniprot IDs		A7J992 Q8WWQ0
PDB IDs		3MB3
Enriched GO Terms of Interacting Partners?		Microtubule Depolymerization Positive Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glucose Import In Response To Insulin Stimulus Positive Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Beta-oxidation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Glucose Import In Response To Insulin Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Phosphatidylinositol 3-kinase Signaling Microtubule-based Process Positive Regulation Of Insulin Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Positive Regulation Of Lipid Catabolic Process Cellular Response To Growth Hormone Stimulus Neuron Projection Development Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Glucose Metabolic Process Neuron Development Regulation Of Glycogen Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Insulin Secretion Protein Kinase B Signaling Response To Growth Hormone Microtubule Polymerization Or Depolymerization Negative Regulation Of Peptide Secretion Positive Regulation Of Mesenchymal Cell Proliferation System Development Positive Regulation Of Glucose Import Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Glucose Transport Regulation Of Phosphatidylinositol 3-kinase Activity Neuron Differentiation JAK-STAT Cascade Cell Projection Organization 'de Novo' Posttranslational Protein Folding Regulation Of Lipid Catabolic Process Regulation Of Lipid Kinase Activity 'de Novo' Protein Folding Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Hormone Secretion Multicellular Organismal Development Regulation Of Glucose Import Anatomical Structure Development Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Stem Cell Proliferation Regulation Of Generation Of Precursor Metabolites And Energy
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