STX17 and ERP44

		STX17	ERP44
Description		syntaxin 17	endoplasmic reticulum protein 44
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GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Autophagosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane COPII-coated ER To Golgi Transport Vesicle Smooth Endoplasmic Reticulum Membrane HOPS Complex SNARE Complex Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Autolysosome Membrane	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Protein Kinase Binding Protein Phosphatase Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Autophagy Golgi Organization Vesicle-mediated Transport Autophagosome Membrane Docking Protein Localization To Phagophore Assembly Site Vesicle Docking Autophagosome-lysosome Fusion Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Autophagosome Maturation	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis
Pathways		COPII-mediated vesicle transport	Neutrophil degranulation
Drugs
Diseases
GWAS		Alopecia areata ( 20596022) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223)	Preeclampsia ( 23551011)
Interacting Genes		22 interacting genes: AURKA BUB1 CDH1 CTNNA1 DLC1 EGFR KRAS MAP2K4 MIS18A MLH1 MLH3 MSH2 NRAS ODC1 PTPN12 PTPN2 RB1 SMAD4 SNAP29 SRC STK11 TLR2	3 interacting genes: ERO1A ERO1B ITPR1
Entrez ID		55014	23071
HPRD ID		05013	10290
Ensembl ID		ENSG00000136874	ENSG00000023318
Uniprot IDs		P56962	A0A384MEE7 Q9BS26
PDB IDs		4WY4 7BV4 7BV6	2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?		Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Mismatched DNA Binding Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Developmental Process ATP-dependent DNA Damage Sensor Activity Chiasma Regulation Of Developmental Process Apoptotic Signaling Pathway Reproductive Process Cytosol Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cell Development Mismatch Repair Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Apoptotic Process Negative Regulation Of ERBB Signaling Pathway Guanine/thymine Mispair Binding Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Apoptotic Process Negative Regulation Of Programmed Cell Death MAPK Cascade Programmed Cell Death Cellular Response To Indole-3-methanol Focal Adhesion Mismatch Repair Complex Cell Death Regulation Of Nervous System Development Negative Regulation Of Cell Differentiation Response To Indole-3-methanol Regulation Of Cell Population Proliferation LRR Domain Binding Positive Regulation Of Isotype Switching To IgA Isotypes Centromeric DNA Binding Cell Population Proliferation Nucleotide Binding Negative Regulation Of Nervous System Development Protein Kinase Activity ATP Binding Animal Organ Development Negative Regulation Of Signal Transduction Signal Transduction Regulation Of Protein Localization To Nucleus Anatomical Structure Morphogenesis Flotillin Complex Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Chromosome Organization Negative Regulation Of Cell Communication	Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization
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