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SLC35F6 and ACP5
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SLC35F6
ACP5
Gene Name
solute carrier family 35, member F6
acid phosphatase 5, tartrate resistant
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Lysosomal Membrane
Integral Component Of Membrane
Extracellular Vesicular Exosome
Lysosome
Cytosol
Integral Component Of Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Acid Phosphatase Activity
Ferrous Iron Binding
Ferric Iron Binding
Biological Process
Transport
Positive Regulation Of Cell Proliferation
Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Riboflavin Metabolic Process
Dephosphorylation
Response To Lipopolysaccharide
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Interleukin-12 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Superoxide Anion Generation
Response To Cytokine
Small Molecule Metabolic Process
Negative Regulation Of Nitric Oxide Biosynthetic Process
Bone Resorption
Negative Regulation Of Inflammatory Response
Defense Response To Gram-positive Bacterium
Bone Morphogenesis
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Vitamin B2 (riboflavin) metabolism
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Metabolism of water-soluble vitamins and cofactors
Defective MUT causes methylmalonic aciduria mut type
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in vitamin and cofactor metabolism
Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Multiple sclerosis (severity) (
19010793
)
Protein-Protein Interactions
14 interactors:
ACP5
ACP6
ALDH2
HMP19
KIAA0087
KIAA0232
MS4A7
NDUFA4L2
OAT
PSMG2
SEC11A
SEPHS1
SERPINH1
TBPL1
11 interactors:
EGR2
GPC4
MAPK9
PDCD5
PPP2CB
RPA2
SLC35F6
SNRNP40
SPP1
TNFSF10
ZBTB16
Entrez ID
54978
54
HPRD ID
12808
01374
Ensembl ID
ENSG00000213699
ENSG00000102575
Uniprot IDs
B4DLH2
Q8N357
P13686
PDB IDs
1WAR
2BQ8
Enriched GO Terms of Interacting Partners
?
Regulation Of Mitochondrion Organization
Regulation Of Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Cell Death
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of Peptidase Activity
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Proteolysis
Positive Regulation Of Mitochondrion Organization
Response To Organic Substance
Apoptotic Mitochondrial Changes
Rhombomere 5 Formation
Rhombomere 3 Formation
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane
Negative Regulation Of Chaperone-mediated Protein Folding
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Rhombomere 3 Morphogenesis
Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Regulation Of Cellular Component Organization
Zymogen Activation
Regulation Of Signaling
Brain Segmentation
Regulation Of Protein Targeting To Mitochondrion
Rhombomere 3 Development
Rhombomere 5 Development
Cellular Response To Growth Factor Stimulus
Rhombomere Morphogenesis
Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of NK T Cell Differentiation
DNA Recombinase Assembly
JUN Phosphorylation
Response To Growth Factor
Cellular Response To Stimulus
Positive Regulation Of Prostaglandin Biosynthetic Process
Male Germ-line Stem Cell Asymmetric Division
Tagcloud
?
13qter
9p
cckbr
cholecystokinin
chro
chromosomes
converter
eleven
ends
fall39
glycoprotein
integrin
itgam
itgbeta2
linkage
mapping
mu
opioid
oprm1
pc1
pellucida
rbp3
retinol
rflp
rnr1
ssc
swine
zona
zp1
Tagcloud (Difference)
?
13qter
9p
cckbr
cholecystokinin
chro
chromosomes
converter
eleven
ends
fall39
glycoprotein
integrin
itgam
itgbeta2
linkage
mapping
mu
opioid
oprm1
pc1
pellucida
rbp3
retinol
rflp
rnr1
ssc
swine
zona
zp1
Tagcloud (Intersection)
?