ACP5 and SLC35F6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ACP5	SLC35F6
Description		acid phosphatase 5, tartrate resistant	solute carrier family 35 member F6
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Cytosol Membrane	Nucleoplasm Mitochondrion Lysosome Lysosomal Membrane Cytosol Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Acid Phosphatase Activity Ferrous Iron Binding Ferric Iron Binding Hydrolase Activity Metal Ion Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Nitric Oxide Biosynthetic Process Negative Regulation Of Macrophage Cytokine Production Response To Lipopolysaccharide Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Superoxide Anion Generation Response To Cytokine Superoxide Anion Generation Negative Regulation Of Nitric Oxide Biosynthetic Process Bone Resorption Negative Regulation Of Inflammatory Response Defense Response To Gram-positive Bacterium Bone Morphogenesis	Positive Regulation Of Cell Population Proliferation Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Pathways		Vitamin B2 (riboflavin) metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Multiple sclerosis (severity) ( 19010793)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: BCL2L13 EGR2 GPC4 MAPK9 PDCD5 PPP2CB RPA2 SLC35F6 SNRNP40 SPP1 TNFSF10 ZBTB16	22 interacting genes: ACP5 ACP6 ALDH2 AQP6 CBARP CERS4 COXFA4L2 FOLR1 GJA8 GPR152 KIAA0087 KIAA0232 MS4A7 NSG2 OAT PSMG2 SEC11A SEPHS1 SERPINH1 TBPL1 TIMMDC1 TMEM14B
Entrez ID		54	54978
HPRD ID		01374	12808
Ensembl ID		ENSG00000102575	ENSG00000213699
Uniprot IDs		P13686	Q8N357
PDB IDs		1WAR 2BQ8
Enriched GO Terms of Interacting Partners?		Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Mitochondrion Organization Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury	Acid Phosphatase Activity
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