ACP5

Name	acid phosphatase 5, tartrate resistant
Structure
Interactors	12 interactors: BCL2L13 EGR2 GPC4 MAPK9 PDCD5 PPP2CB RPA2 SLC35F6 SNRNP40 SPP1 TNFSF10 ZBTB16
GO Annotations	Cellular Component	Lysosome Cytosol Membrane
	Molecular Function	Acid Phosphatase Activity Ferrous Iron Binding Ferric Iron Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Nitric Oxide Biosynthetic Process Negative Regulation Of Macrophage Cytokine Production Response To Lipopolysaccharide Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Superoxide Anion Generation Response To Cytokine Superoxide Anion Generation Negative Regulation Of Nitric Oxide Biosynthetic Process Bone Resorption Negative Regulation Of Inflammatory Response Defense Response To Gram-positive Bacterium Bone Morphogenesis
Pathways	Vitamin B2 (riboflavin) metabolism
GWAS	Blood protein levels ( 30072576 ) Multiple sclerosis (severity) ( 19010793 )
Entrez ID	54
HPRD ID	01374
Ensembl ID	ENSG00000102575
Uniprot IDs	P13686
PDB IDs	1WAR 2BQ8
GO Terms Enriched among Interactors ?	Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Mitochondrion Organization Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury