SECISBP2 and ATXN7L3

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SECISBP2	ATXN7L3
Description		SECIS binding protein 2	ataxin 7 like 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Ribonucleoprotein Complex	SAGA Complex Nucleus Transcription Factor TFTC Complex SAGA-type Complex DUBm Complex
	Molecular Function	DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Selenocysteine Insertion Sequence Binding Ribonucleoprotein Complex Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Selenocysteine Incorporation RNA Catabolic Process Translation Striatum Development Forebrain Neuron Development MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Regulation Of DNA Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription
Pathways		Selenocysteine synthesis	HATs acetylate histones
Drugs
Diseases
GWAS		Trunk fat mass ( 28552196)	Bipolar disorder ( 31043756) Height ( 31562340)
Interacting Genes		9 interacting genes: APP ATXN7L3 DMRTB1 FAM168A GOLGA2 QKI RNF10 SMAD9 TRNAU1AP	9 interacting genes: APP H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP6
Entrez ID		79048	56970
HPRD ID		07408	12507
Ensembl ID		ENSG00000187742	ENSG00000087152
Uniprot IDs		A0A1S5UZH3 B4DR97 B4DZC7 Q96T21 Q9H948	Q14CW9
PDB IDs		7ZJW 7ZJX	2KKT
Enriched GO Terms of Interacting Partners?		Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Nervous System Process Positive Regulation Of Myelination Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Myelination Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Internal N(7)-methylguanine-containing RNA Reader Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Translation Regulation Of Protein Import Regulation Of MiRNA Metabolic Process Regulation Of Gene Expression Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Biosynthetic Process Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Myofibroblast Contraction Regulation Of Gliogenesis Negative Regulation Of MiRNA Catabolic Process Positive Regulation Of Base-excision Repair DUBm Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response	Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Antibacterial Humoral Response Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Glial Cell Development Regulation Of Endocytosis Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Trans-Golgi Network Membrane Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Defense Response To Gram-positive Bacterium G Protein-coupled Receptor Binding Protein Heterodimerization Activity Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Endocytic Vesicle Membrane Cysteine-type Deubiquitinase Activity Protein Deubiquitination Protein Modification By Small Protein Removal Nucleosome Structural Constituent Of Chromatin Membrane Curvature Sensor Activity Selenocysteine Insertion Sequence Binding Dephospho-CoA Kinase Activity Intermediate-density Lipoprotein Particle Protein Metabolic Process Axon Midline Choice Point Recognition Recycling Endosome Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding
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