RBMS3 and YTHDF1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		RBMS3	YTHDF1
Description		RNA binding motif single stranded interacting protein 3	YTH N6-methyladenosine RNA binding protein F1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex	P-body Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Poly(A) Binding Poly(U) RNA Binding MRNA 3'-UTR AU-rich Region Binding	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	Defense Response To Tumor Cell Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Translation Negative Regulation Of Canonical Wnt Signaling Pathway	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Antisaccade task score ( 31596458) Basal ganglia growth ( 29682794) Bipolar disorder ( 33169155) Bone mineral density ( 17903296) Breast size ( 22747683) Central corneal thickness ( 32528159) Chronic obstructive pulmonary disease ( 30804561) Cleft lip with or without cleft palate (maternal periconceptional alcohol intake interaction) ( 29535761) Dental caries ( 23259602) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Diastolic blood pressure ( 30224653) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 28552196) Intracranial aneurysm ( 29531279) Lung cancer in ever smokers ( 28604730) Lung function (FEV1/FVC) ( 30061609 30804560) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (antihistamines for systemic use) ( 31015401) Night sleep phenotypes ( 27126917) Nonunion in individuals with fractures ( 30680360) Periodontal disease-related phenotype (Socransky) ( 26962152) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Response to radiotherapy in cancer (late toxicity) ( 24785509) Schizophrenia ( 30285260)	Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		1 interacting genes: YTHDF1	42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34
Entrez ID		27303	54915
HPRD ID		16155	11691
Ensembl ID		ENSG00000144642	ENSG00000149658
Uniprot IDs		C9JIJ9 Q6XE24	Q9BYJ9
PDB IDs			4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?		N6-methyladenosine-containing RNA Reader Activity Regulation Of Axon Guidance Regulation Of Antigen Processing And Presentation Regulation Of Long-term Synaptic Potentiation Stress Granule Assembly Positive Regulation Of Translational Initiation Regulation Of Translational Initiation Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization P-body Cytoplasmic Stress Granule Ribosome Binding Memory Learning Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation	Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding
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