MKS1 and DDX24

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MKS1	DDX24
Gene Name		Meckel syndrome, type 1	DEAD (Asp-Glu-Ala-Asp) box helicase 24
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Membrane TCTN-B9D Complex Ciliary Basal Body	Nucleolus Membrane
	Molecular Function	Protein Binding	RNA Helicase Activity ATP Binding Poly(A) RNA Binding
	Biological Process	Organelle Organization Cilium Assembly Branching Morphogenesis Of An Epithelial Tube Cilium Morphogenesis	RNA Metabolic Process
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Signaling by Hedgehog Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: DDX24 TMEM67	31 interactors: BCS1L BRCA1 C9orf9 CSNK2A1 EIF3E EP300 FADD GIT1 GLRA2 HSP90AB1 HSPA5 IDO1 ITGB3BP MKS1 MRPL4 NRXN2 PAFAH1B3 PIN1 POLA2 PRF1 PTPN23 RAE1 SPTAN1 SUMO1 TERF1 TERF2 TERF2IP TMEM9B TPI1 TRDMT1 VDAC3
Entrez ID		54903	57062
HPRD ID		07900	05860
Ensembl ID		ENSG00000011143	ENSG00000089737
Uniprot IDs		F5H5Y8 Q9NXB0	G3V529 Q4V9L5 Q9GZR7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centrosome Duplication Regulation Of Centrosome Duplication ER-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of Centrosome Cycle	Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Maintenance RNA-dependent DNA Replication Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Regulation Of Organelle Organization Telomere Capping DNA Replication Protein Localization To Chromosome, Telomeric Region Cell Cycle Regulation Of Cell Cycle Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Replicative Cell Aging Response To Stimulus Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Component Organization Cellular Response To Cytokine Stimulus Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Apoptotic Process Mitotic Cell Cycle Process Programmed Cell Death Regulation Of Protein Metabolic Process Response To Cytokine Organelle Organization Cell Cycle Process DNA Metabolic Process Cell Death Death Regulation Of Cytokine-mediated Signaling Pathway Response To External Stimulus Negative Regulation Of DNA Metabolic Process Developmental Process Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Apoptotic Process Regulation Of Signal Transduction
Tagcloud ?		adamts16 ambiguous biopsies capacities cen17 cish commercially concordance copy deserves diploidy embedded expensive fish french gold ish lap3 mrm1 paraffin participating polysomy primer qpcr sish sstr2 taok1 tsn utp6	abrogation box consequent consistently dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly
Tagcloud (Difference) ?		adamts16 ambiguous biopsies capacities cen17 cish commercially concordance copy deserves diploidy embedded expensive fish french gold ish lap3 mrm1 paraffin participating polysomy primer qpcr sish sstr2 taok1 tsn utp6	abrogation box consequent consistently dead degradation elicit helicase interacts mdm2 mediates networks nonproteolytic nucleolar polyubiquitylation pre preribosomal processing promoted proteasomal ribonucleoprotein rrna rrnp stabilization steps triggers ubiquitylation unexpected unexpectedly
Tagcloud (Intersection) ?