SLC66A1 and GPRC5D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC66A1	GPRC5D
Description		solute carrier family 66 member 1	G protein-coupled receptor class C group 5 member D
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Organelle Membrane	Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	L-histidine Transmembrane Transporter Activity Protein Binding Basic Amino Acid Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Amino Acid Transport Lysine Transport Transmembrane Transport Intracellular Amino Acid Homeostasis L-histidine Transmembrane Transport L-lysine Transmembrane Transport L-arginine Transmembrane Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: AQP6 GJA5 GJA8 GJC1 GPR152 GPRC5D NINJ2 SLC35H1 SLC39A2 SLC39A9	30 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1
Entrez ID		54896	55507
HPRD ID		17896	07604
Ensembl ID		ENSG00000040487	ENSG00000111291
Uniprot IDs		A0A024RAA1 Q6ZP29	Q9NZD1
PDB IDs			8YZK 9IMA
Enriched GO Terms of Interacting Partners?		Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Gap Junction Channel Activity SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Connexin Complex Transmembrane Transport Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication Gap Junction Assembly Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell-cell Junction Assembly Cell Communication By Electrical Coupling Metal Ion Transmembrane Transporter Activity Cell Communication Involved In Cardiac Conduction Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Membrane Zinc Ion Transmembrane Transport Zinc Ion Transport Cell-cell Junction Organization Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Intercalated Disc Nitrate Transmembrane Transporter Activity Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Cell Junction Assembly Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Monoatomic Ion Transmembrane Transport Cardiac Muscle Tissue Development Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation Atrial Cardiac Muscle Cell To AV Node Cell Communication Regulation Of Cellular Response To Testosterone Stimulus	Membrane
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