SLC66A1 and SLC39A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC66A1	SLC39A2
Description		solute carrier family 66 member 1	solute carrier family 39 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Organelle Membrane	Plasma Membrane Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	L-histidine Transmembrane Transporter Activity Protein Binding Basic Amino Acid Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport Lysine Transport Transmembrane Transport Intracellular Amino Acid Homeostasis L-histidine Transmembrane Transport L-lysine Transmembrane Transport L-arginine Transmembrane Transport	Monoatomic Ion Transport Zinc Ion Transport Metal Ion Transport Keratinocyte Differentiation Transmembrane Transport Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport
Pathways		Miscellaneous transport and binding events	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: AQP6 GJA5 GJA8 GJC1 GPR152 GPRC5D NINJ2 SLC35H1 SLC39A2 SLC39A9	52 interacting genes: AQP1 AQP6 ARL13B ARLN BCL2L2 BTN2A2 C3orf52 CD79A CLCA4 CNR2 COL4A5 COMT CREB3L1 CXCR2 CYB561 EHHADH EMC6 FAM209A FCER1G FXYD3 FXYD6 GJA8 GPR152 GPR42 KCNAB1 KCNAB2 LY6G6C MFSD6 MS4A13 PLN PNLIPRP1 SEC22A SLC18A1 SLC30A2 SLC30A8 SLC39A1 SLC39A9 SLC66A1 SLC7A1 SSMEM1 ST6GAL2 STATH TMEM107 TMEM14B TMEM229B TMEM237 TMEM54 TMEM60 TMEM86A TRHR UPK1B YIPF6
Entrez ID		54896	29986
HPRD ID		17896	15385
Ensembl ID		ENSG00000040487	ENSG00000165794
Uniprot IDs		A0A024RAA1 Q6ZP29	Q9NP94
PDB IDs
Enriched GO Terms of Interacting Partners?		Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Gap Junction Channel Activity SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling Connexin Complex Transmembrane Transport Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling SA Node Cell To Atrial Cardiac Muscle Cell Communication AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication Gap Junction Assembly Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cell-cell Junction Assembly Cell Communication By Electrical Coupling Metal Ion Transmembrane Transporter Activity Cell Communication Involved In Cardiac Conduction Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Membrane Zinc Ion Transmembrane Transport Zinc Ion Transport Cell-cell Junction Organization Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Intercalated Disc Nitrate Transmembrane Transporter Activity Gap Junction Channel Activity Involved In Purkinje Myocyte-ventricular Cardiac Muscle Cell Electrical Coupling Mitral Valve Development Septum Primum Development Gap Junction Channel Activity Involved In Atrial Cardiac Muscle Cell-AV Node Cell Electrical Coupling Atrial Ventricular Junction Remodeling Gap Junction Channel Activity Involved In Bundle Of His Cell-Purkinje Myocyte Electrical Coupling Positive Regulation Of Cell Communication By Chemical Coupling Atrial Cardiac Muscle Cell To AV Node Cell Communication By Electrical Coupling Cell Junction Assembly Vasomotion Purkinje Myocyte To Ventricular Cardiac Muscle Cell Communication By Electrical Coupling Regulation Of Purkinje Myocyte Action Potential Monoatomic Ion Transmembrane Transport Cardiac Muscle Tissue Development Plasma Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Foramen Ovale Closure Bundle Of His Cell To Purkinje Myocyte Communication By Electrical Coupling Regulation Of Bundle Of His Cell Action Potential Cell Communication By Chemical Coupling Pulmonary Valve Formation Atrial Cardiac Muscle Cell To AV Node Cell Communication Regulation Of Cellular Response To Testosterone Stimulus	Membrane Transmembrane Transport Monoatomic Ion Transport Zinc Ion Transmembrane Transporter Activity Inorganic Ion Transmembrane Transport Zinc Ion Transport Zinc Ion Transmembrane Transport Metal Ion Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Lysine Transport Potassium Ion Transport Inorganic Cation Transmembrane Transport Protein Binding Plasma Membrane Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity L-histidine Transmembrane Transport Zinc:proton Antiporter Activity Monoamine Transport Intracellular Zinc Ion Homeostasis Monoatomic Cation Transmembrane Transport L-lysine Transmembrane Transport Organic Cation Transport Ion Channel Regulator Activity Renal Water Transport Norepinephrine Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane Neural Tube Patterning Channel Activity Ammonium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Basic Amino Acid Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity Ammonium Transmembrane Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Response To Zinc Ion Aromatic Amino Acid Transport Zinc Ion Import Into Organelle L-arginine Transmembrane Transport Transport Vesicle Membrane Serotonin Transport Azole Transmembrane Transport Juxtaparanode Region Of Axon Alcohol Dehydrogenase (NADP+) Activity External Side Of Plasma Membrane Water Channel Activity Carbon Dioxide Transport
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