SYTL2 and RAB27B

Number of citations of the paper that reports this interaction (PMID 11980908)
70

Data Source:
BioGRID (two hybrid)

		SYTL2	RAB27B
Gene Name		synaptotagmin-like 2	RAB27B, member RAS oncogene family
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Melanosome Exocytic Vesicle	Golgi Stack Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Rab GTPase Binding Phosphatase Binding Neurexin Family Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Negative Regulation Of Phosphatase Activity Vesicle-mediated Transport Positive Regulation Of Mucus Secretion	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: FBXO25 MTERF1 NRXN1 PPP1CA RAB27A RAB27B	8 interactors: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		54843	5874
HPRD ID		10260	04846
Ensembl ID		ENSG00000137501	ENSG00000041353
Uniprot IDs		Q9HCH5	O00194
PDB IDs		3BC1	2F7S
Enriched GO Terms of Interacting Partners?		Multivesicular Body Sorting Pathway Vesicle Localization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Rab Protein Signal Transduction Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Organelle Localization Vesicle Docking Secretion By Cell Membrane Docking Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation Termination Of Mitochondrial Transcription Gamma-aminobutyric Acid Receptor Clustering Complement-dependent Cytotoxicity Pigmentation Secretion Regulation Of Secretion Protein Secretion Multivesicular Body Organization Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Cytotoxic T Cell Degranulation Regulation Of Exocytosis Gephyrin Clustering Synaptic Vesicle Clustering Exosomal Secretion Neuronal Signal Transduction Establishment Of Vesicle Localization N-methyl-D-aspartate Receptor Clustering Vocal Learning Ras Protein Signal Transduction Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Natural Killer Cell Degranulation Regulation Of Cellular Localization Synapse Maturation Regulation Of Grooming Behavior Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering T Cell Mediated Cytotoxicity Regulation Of Glycogen Catabolic Process Receptor Localization To Synapse Presynaptic Membrane Organization Auditory Behavior Establishment Of Organelle Localization	Exocytosis Secretion By Cell Secretion Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Positive Regulation Of Secretion Protein Localization Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Transport Transport Positive Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Deoxyhypusine Biosynthetic Process From Spermidine Granuloma Formation Spermidine Catabolic Process Multivesicular Body Sorting Pathway Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Positive Regulation Of Protein Secretion Glucose Homeostasis Natural Killer Cell Degranulation Regulation Of Cellular Localization Chronic Inflammatory Response Positive Regulation Of Mucus Secretion Germinal Center Formation Positive Regulation Of Protein Transport Regulation Of Mucus Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Protein Secretion Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Mast Cell Degranulation Regulation Of Cell Activation Polyamine Metabolic Process Leukocyte Mediated Cytotoxicity Regulation Of Mast Cell Activation Melanocyte Differentiation Negative Regulation Of Insulin Secretion Regulation Of Regulated Secretory Pathway Melanosome Localization Leukocyte Degranulation Negative Regulation Of Peptide Secretion
Tagcloud ?			7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Difference) ?			7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Intersection) ?