TBC1D13 and PLIN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBC1D13	PLIN3
Description		TBC1 domain family member 13	perilipin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Cadherin Binding
	Biological Process	Intracellular Protein Transport Regulation Of Cilium Assembly	Positive Regulation Of Triglyceride Storage Vesicle-mediated Transport Lipid Storage Cellular Response To Glucose Starvation Lipid Droplet Disassembly
Pathways		TBC/RABGAPs	Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle
Drugs			Idursulfase Galsulfase
Diseases
GWAS		Blood metabolite levels ( 26401656) HDL cholesterol levels ( 32203549) Serum metabolite levels ( 33031748)	Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)
Interacting Genes		5 interacting genes: ARHGEF5 PLIN3 SPDYE4 TEPSIN ZNF618	33 interacting genes: ABHD4 ABHD5 APP CCNC CEBPA CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C
Entrez ID		54662	10226
HPRD ID		18163	04080
Ensembl ID		ENSG00000107021	ENSG00000105355
Uniprot IDs		A0A024R8C8 B3KNG3 B4DHM6 Q9NVG8	A0A140VJN8 O60664
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Import Myeloid Dendritic Cell Chemotaxis Regulation Of Protein Import Positive Regulation Of Triglyceride Storage Coated Vesicle Membrane	Collateral Sprouting In Absence Of Injury Insulin Receptor Binding Regulation Of Long-term Neuronal Synaptic Plasticity Vesicle-mediated Transport Identical Protein Binding Retromer, Tubulation Complex Leptin Receptor Binding Lipid Droplet Trans-Golgi Network Membrane Lamellipodium Morphogenesis Regulation Of Neuronal Synaptic Plasticity Endocytosis Nuclear Envelope Lumen Retromer Complex Binding Transferrin Receptor Binding Regulation Of Synaptic Vesicle Priming Lysophosphatidic Acid Acyltransferase Activity Intracellular Transport Receptor-mediated Endocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Collateral Sprouting Early Endosome To Golgi Transport Neuromuscular Junction Endosome Establishment Of Protein Localization Neuron Projection Terminus Regulation Of Neurotransmitter Uptake Retromer Complex Protein Transport Retrograde Transport, Endosome To Golgi Midbody Abscission Transport Vesicle Cytoplasmic Vesicle Import Into Cell Mitotic Cytokinetic Process
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