HDL3 and BGN

Number of citations of the paper that reports this interaction (PMID 11145944)
7

Data Source:
BioGRID (pull down)

		HDL3	BGN
Gene Name		Huntington-like neurodegenerative disorder 2	biglycan
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Region Proteinaceous Extracellular Matrix Golgi Lumen Cell Surface Transport Vesicle Extracellular Matrix Sarcolemma Lysosomal Lumen Extracellular Vesicular Exosome
	Molecular Function		Extracellular Matrix Structural Constituent Glycosaminoglycan Binding Extracellular Matrix Binding
	Biological Process		Blood Vessel Remodeling Carbohydrate Metabolic Process Biological_process Pathogenesis Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism CS/DS degradation Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora ECM proteoglycans Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Dermatan sulfate biosynthesis Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: BGN	16 interactors: APOB APP BMP4 COL1A1 COL1A2 COL2A1 COL4A2 DAG1 ELN HDL3 JPH3 MFAP2 PLA2G1B TGFB1 TNF WISP1
Entrez ID		53369	633
HPRD ID			02359
Ensembl ID			ENSG00000182492
Uniprot IDs			B4DNL4 P21810 Q8NAB7
PDB IDs
Enriched GO Terms of Interacting Partners?		Dermatan Sulfate Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Chondroitin Sulfate Catabolic Process Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Blood Vessel Remodeling Peptide Cross-linking Glycosaminoglycan Catabolic Process Proteoglycan Biosynthetic Process Chondroitin Sulfate Metabolic Process Glycosaminoglycan Biosynthetic Process Proteoglycan Metabolic Process Tissue Remodeling Glycosaminoglycan Metabolic Process Pathogenesis Sulfur Compound Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Glycoprotein Biosynthetic Process Glycoprotein Metabolic Process Monocarboxylic Acid Metabolic Process	Extracellular Matrix Organization Extracellular Structure Organization Locomotion Anatomical Structure Morphogenesis Multicellular Organismal Metabolic Process Movement Of Cell Or Subcellular Component Extracellular Matrix Disassembly Response To External Stimulus Organ Morphogenesis Protein Localization To Nucleus Collagen Catabolic Process Cell Morphogenesis Involved In Differentiation Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Leukocyte Migration System Development Response To Organic Substance Cellular Response To Organic Substance Negative Regulation Of Myoblast Differentiation Response To Hormone Cellular Response To Growth Factor Stimulus Bone Morphogenesis Chemotaxis Multicellular Organismal Development Response To Growth Factor Immune System Process Anatomical Structure Development Cell Morphogenesis Organ Development Salivary Gland Morphogenesis Endochondral Ossification Gland Morphogenesis Regulation Of Myoblast Differentiation Salivary Gland Development Negative Regulation Of Muscle Cell Differentiation Cellular Response To Acid Chemical Cellular Response To Lipid Cellular Response To Transforming Growth Factor Beta Stimulus Blood Coagulation Hemostasis Developmental Process Exocrine System Development Response To Transforming Growth Factor Beta Platelet Activation Cartilage Development Common-partner SMAD Protein Phosphorylation Cell Migration Cellular Response To Amino Acid Stimulus Collagen Fibril Organization Cardiovascular System Development
Tagcloud ?		aggregated apoai apoj barrier biotinylated cerebrospinal circulation complexed composed demonstration depleted fibrils fractions immunoprecipitation lesser lipoprotein lipoproteins named neuritic physiologic plaques plasma possibly recovered sa supernatants traced vessels vhdl	bambara bean beverage bgnm bgns boiled cow cowpea crop crops drought eaten fermented groundnut irritable legume legumes neglected nutritious probiotic probiotics relish roasted salted snack subterraenea traced verdc vigna
Tagcloud (Difference) ?		aggregated apoai apoj barrier biotinylated cerebrospinal circulation complexed composed demonstration depleted fibrils fractions immunoprecipitation lesser lipoprotein lipoproteins named neuritic physiologic plaques plasma possibly recovered sa supernatants vessels vhdl	bambara bean beverage bgnm bgns boiled cow cowpea crop crops drought eaten fermented groundnut irritable legume legumes neglected nutritious probiotic probiotics relish roasted salted snack subterraenea verdc vigna
Tagcloud (Intersection) ?		traced