PLAT and GML

		PLAT	GML
Description		plasminogen activator, tissue type	glycosylphosphatidylinositol anchored molecule like
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Cell Surface Secretory Granule Extracellular Matrix Apical Part Of Cell Extracellular Exosome Serine Protease Inhibitor Complex Schaffer Collateral - CA1 Synapse Glutamatergic Synapse	Plasma Membrane Membrane Extrinsic Component Of Membrane Side Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity Phosphoprotein Binding
	Biological Process	Response To Hypoxia Proteolysis Blood Coagulation Negative Regulation Of Plasminogen Activation Smooth Muscle Cell Migration Zymogen Activation Plasminogen Activation Protein Modification Process Fibrinolysis Negative Regulation Of Proteolysis Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Fibrinolysis Prevention Of Polyspermy Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission	Apoptotic Process Negative Regulation Of Cell Population Proliferation DNA Damage Response, Signal Transduction By P53 Class Mediator
Pathways		Signaling by PDGF Dissolution of Fibrin Clot
Drugs		Aminocaproic acid Iloprost Human C1-esterase inhibitor 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID Dexibuprofen Conestat alfa
Diseases
GWAS		Blood protein levels ( 30072576) Plasma plasminogen activator levels ( 24578379) Systemic lupus erythematosus ( 28714469)	Medication use (calcium channel blockers) ( 31015401)
Interacting Genes		28 interacting genes: ANXA2 APP CALR CKAP4 CLEC3B F10 FGA FN1 GRIN1 HMGB1 KRT8 LAMA1 LAMA3 LRP1 LRP1B MAPK1 MAPK3 MTDH PDGFC PLAU PLG SERPINA5 SERPINE1 SERPING1 SERPINI1 SNCA SPARC VDAC1
Entrez ID		5327	2765
HPRD ID		01419	03844
Ensembl ID		ENSG00000104368	ENSG00000104499
Uniprot IDs		B4DN26 P00750	Q99445
PDB IDs		1A5H 1BDA 1PK2 1PML 1RTF 1TPG 1TPK 1TPM 1TPN 5BRR 5ZLZ
Enriched GO Terms of Interacting Partners?		Fibrinolysis Extracellular Space Regulation Of Locomotion Regulation Of Cell Migration Platelet Alpha Granule Lumen Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Motility Extracellular Region Positive Regulation Of Locomotion Endoplasmic Reticulum Lumen Negative Regulation Of Blood Coagulation Extracellular Matrix Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Regulation Of Blood Coagulation Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Wound Healing Serine-type Endopeptidase Inhibitor Activity Regulation Of Plasminogen Activation Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Platelet Alpha Granule Regulation Of Cell Adhesion Cell Surface Regulation Of Response To Wounding Regulation Of Multicellular Organismal Process Regulation Of Vesicle-mediated Transport Regulation Of Protein Maturation Positive Regulation Of Signaling Extracellular Exosome Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of Endocytosis Basement Membrane Plasma Membrane Negative Regulation Of Fibrinolysis Regulation Of Body Fluid Levels Positive Regulation Of Cell Communication Blood Coagulation Positive Regulation Of Cellular Component Organization Coagulation Protease Binding Hemostasis Peptidase Inhibitor Activity Regulation Of Endocytosis Negative Regulation Of Multicellular Organismal Process Calcium Ion Binding	Acetylcholine Receptor Binding Acetylcholine Receptor Inhibitor Activity Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Smooth Muscle Cell Migration Prevention Of Polyspermy Trans-synaptic Signaling By BDNF Serine Protease Inhibitor Complex Plasminogen Activation Negative Regulation Of Plasminogen Activation Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Regulation Of Fertilization Regulation Of Fibrinolysis Regulation Of Plasminogen Activation Fibrinolysis Host-mediated Suppression Of Symbiont Invasion Positive Regulation Of Blood Coagulation Muscle Cell Migration Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Positive Regulation Of Coagulation Platelet-derived Growth Factor Receptor Signaling Pathway Zymogen Activation Phosphoprotein Binding Acetylcholine Receptor Signaling Pathway Postsynaptic Signal Transduction Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Regulation Of Protein Processing Regulation Of Protein Maturation Positive Regulation Of Wound Healing Negative Regulation Of Reproductive Process Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Apical Part Of Cell Host-mediated Perturbation Of Symbiont Process Schaffer Collateral - CA1 Synapse Coagulation Blood Coagulation Hemostasis Secretory Granule Cell Surface Receptor Signaling Pathway Modulation Of Process Of Another Organism Side Of Membrane Serine-type Peptidase Activity Extracellular Region Regulation Of Wound Healing Negative Regulation Of Proteolysis
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