PIK3CA and PDE4D

  • Number of citations of the paper that reports this interaction (PMID 10571082)
  • 8
  • Data Source:
  • BioGRID (far western blotting)

PIK3CA

PDE4D

Gene Name phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha phosphodiesterase 4D, cAMP-specific
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 43 interactors: ADAP1 AMBP APLP2 APPL1 ATPIF1 ATR DDX5 DNAJB6 FASLG FTL GABRB1 GNAQ GRIN2B HRAS IL3 IRS2 IRS4 ITIH1 KRAS LCK MRAS NEDD9 NRAS PDE4D PDGFRB PIK3R1 PIK3R3 PRKCD RASD2 RASGRP3 RPS20 RPS6KB1 SGK1 SH3KBP1 SLC9A3R1 SLC9A3R2 SMAD2 SMAD3 SQSTM1 STAT1 TICAM1 UFD1L VARS2 25 interactors: ABL1 AKAP6 APP ARRB1 ARRB2 COIL CSNK1A1 FYN GNB2L1 GOLGA8EP GOLGA8F GRB2 GSK3B LYN MAGEA6 MAPK1 MDM2 PAFAH1B1 PDE4DIP PIAS4 PIK3CA PRKACA SPTBN1 SRC TRAF1
Entrez ID 5290 5144
HPRD ID 01382 02530
Ensembl ID ENSG00000113448
Uniprot IDs P42336 Q08499
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM 1E9K 1MKD 1OYN 1PTW 1Q9M 1TB7 1TBB 1XOM 1XON 1XOQ 1XOR 1Y2B 1Y2C 1Y2D 1Y2E 1Y2K 1ZKN 2FM0 2FM5 2PW3 2QYN 3G4G 3G4I 3G4K 3G4L 3G58 3IAD 3IAK 3K4S 3SL3 3SL4 3SL5 3SL6 3SL8 3V9B
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
acth  adrenal  adrenocortical  adrenocorticotropin  belongs  biosynthesis  camp  confers  cortisol  cyp17a1  dbhs  exoribonuclease  export  facilitating  glucocorticoid  h295r  isoforms  nono  p54nrb  pde11a  pde2a  pde3a  pde3b  pde4a  phosphodiesterase  select  splicing  xrn2 
Tagcloud (Difference) ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
acth  adrenal  adrenocortical  adrenocorticotropin  belongs  biosynthesis  camp  confers  cortisol  cyp17a1  dbhs  exoribonuclease  export  facilitating  glucocorticoid  h295r  isoforms  nono  p54nrb  pde11a  pde2a  pde3a  pde3b  pde4a  phosphodiesterase  select  splicing  xrn2 
Tagcloud (Intersection) ?