PIGY and ABCB4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PIGY	ABCB4
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class Y	ATP-binding cassette, sub-family B (MDR/TAP), member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Intercellular Canaliculus Extracellular Vesicular Exosome
	Molecular Function		ATP Binding Xenobiotic-transporting ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	GPI Anchor Biosynthetic Process	Lipid Metabolic Process Transport Drug Transmembrane Transport Response To Drug Xenobiotic Transport Cellular Lipid Metabolic Process Small Molecule Metabolic Process Transmembrane Transport
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Bipolar disorder ( 22925353)
Protein-Protein Interactions		2 interactors: ABCB4 PIGA	3 interactors: HAX1 PIGY TESK1
Entrez ID		84992	5244
HPRD ID		17492	01371
Ensembl ID			ENSG00000005471
Uniprot IDs		Q3MUY2	P21439
PDB IDs
Enriched GO Terms of Interacting Partners?		Xenobiotic Transport Preassembly Of GPI Anchor In ER Membrane Cellular Lipid Metabolic Process C-terminal Protein Lipidation Drug Transmembrane Transport Lipid Metabolic Process Drug Transport GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process
Tagcloud ?			aberrant absent atp aza carcinogenesis cassette colony cpg deoxycytidine epigenetic epigenetically hallmark head hypermethylation inactivation island lung matching member neck occurred reexpression reversed silenced silencing sub suppressivly tissues zebularine
Tagcloud (Difference) ?			aberrant absent atp aza carcinogenesis cassette colony cpg deoxycytidine epigenetic epigenetically hallmark head hypermethylation inactivation island lung matching member neck occurred reexpression reversed silenced silencing sub suppressivly tissues zebularine
Tagcloud (Intersection) ?