PFDN4 and VBP1

Number of citations of the paper that reports this interaction (PMID 22863883)
15

Data Source:
BioGRID (two hybrid, biochemical)

		PFDN4	VBP1
Gene Name		prefoldin subunit 4	von Hippel-Lindau binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Prefoldin Complex	Nucleus Cytoplasm Prefoldin Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Unfolded Protein Binding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding	Protein Folding Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding	Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: ACTB PFDN2 TUBA4A TUBB VBP1	9 interactors: MKNK2 MSH4 PFDN2 PFDN4 PIK3R3 PNMA1 UBL7 VHL XRCC6
Entrez ID		5203	7411
HPRD ID		05358	02135
Ensembl ID		ENSG00000101132	ENSG00000155959
Uniprot IDs		Q9NQP4	B4DWR3 F5H2A7 P61758
PDB IDs
Enriched GO Terms of Interacting Partners?		'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Protein Folding Protein Polymerization G2/M Transition Of Mitotic Cell Cycle Platelet Activation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Complex Assembly Blood Coagulation Hemostasis Microtubule Cytoskeleton Organization Cellular Component Assembly Cellular Protein Metabolic Process Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Body Fluid Levels Wound Healing Cellular Macromolecular Complex Assembly Leukocyte Mediated Cytotoxicity Mitotic Cell Cycle Process Cell Activation Substantia Nigra Development Response To Wounding Platelet Aggregation Cellular Response To Interleukin-4 Mitotic Cell Cycle Microtubule-based Process Response To Interleukin-4 Innate Immune Response Neural Nucleus Development Protein Metabolic Process Retina Homeostasis	'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding
Tagcloud ?		12p11 13q11 16q24 1p32 20q13 3q21 bacs cdkn1b cgh chromosomes copy cyp24 fstl1 heterozygosity hyperplastic informative loh16 loh9 narrowed overcomes p13 ppp2r3 q25 q32 rip stmn1 sv40 syntenic unappreciated	atpase break coexist dsb e3 hek293t hippel hmsh4 homologous immunocomplex joining ligase lindau meiotic mitotic muts nonhomologous p97 partner polyubiquitination prefoldin proteolysis recombination recombinational repair strand ubiquitination vhl von
Tagcloud (Difference) ?		12p11 13q11 16q24 1p32 20q13 3q21 bacs cdkn1b cgh chromosomes copy cyp24 fstl1 heterozygosity hyperplastic informative loh16 loh9 narrowed overcomes p13 ppp2r3 q25 q32 rip stmn1 sv40 syntenic unappreciated	atpase break coexist dsb e3 hek293t hippel hmsh4 homologous immunocomplex joining ligase lindau meiotic mitotic muts nonhomologous p97 partner polyubiquitination prefoldin proteolysis recombination recombinational repair strand ubiquitination vhl von
Tagcloud (Intersection) ?