WBP11 and CYGB

		WBP11	CYGB
Description		WW domain binding protein 11	cytoglobin
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm Cytosol Nuclear Speck Neuron Projection Neuronal Cell Body
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding	Catalase Activity Peroxidase Activity Superoxide Dismutase Activity Oxygen Carrier Activity Iron Ion Binding Protein Binding Antioxidant Activity Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Fatty Acid Peroxidase Activity Carbon Monoxide Binding Nitrite Reductase Activity Nitric Oxide Dioxygenase Activity, Heme Protein As Donor
	Biological Process	RRNA Processing RNA Processing MRNA Processing RNA Splicing	Response To Hypoxia Response To Oxidative Stress Negative Regulation Of Fibroblast Migration Oxygen Transport Fatty Acid Oxidation Removal Of Superoxide Radicals Negative Regulation Of Collagen Biosynthetic Process Nitric Oxide Metabolic Process Nitric Oxide Catabolic Process Negative Regulation Of Hepatic Stellate Cell Activation
Pathways		mRNA Splicing - Major Pathway	eNOS activation Intracellular oxygen transport
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		37 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CEBPA CTNNBL1 DDX17 DDX5 FOXP1 FYN GIGYF2 GRB2 ITSN1 MCRS1 MORN4 NCK2 NOD2 PCBP4 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRMT2 PRPF40A RBM5 RSPH1 RTN4IP1 RUNX1T1 SEC23A SRC TESC TRAF4 TRIP10 UBASH3A VIM WBP4	6 interacting genes: ARHGAP8 ATP13A2 DDI1 LRATD1 MZT1 PRR5-ARHGAP8
Entrez ID		51729	114757
HPRD ID		18293	06479
Ensembl ID		ENSG00000084463	ENSG00000161544
Uniprot IDs		Q9Y2W2	Q8WWM9
PDB IDs		7ABF 7ABG	1UMO 1URV 1URY 1UT0 1UX9 1V5H 2DC3 3AG0 4B3W
Enriched GO Terms of Interacting Partners?		Nuclear Speck Proline-rich Region Binding Cytosol RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome PTW/PP1 Phosphatase Complex Nucleus RNA Splicing Ribonucleoprotein Complex Binding Cytoplasm Regulation Of RNA Splicing Nucleoplasm MRNA Processing Protein Domain Specific Binding Regulation Of Defense Response Protein-containing Complex Binding Regulation Of Gene Expression Scaffold Protein Binding Entrainment Of Circadian Clock By Photoperiod Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Nuclear Androgen Receptor Binding Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Ephrin Receptor Binding Photoperiodism Entrainment Of Circadian Clock Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process MRNA Metabolic Process Regulation Of Innate Immune Response Regulation Of Programmed Cell Death Positive Regulation Of Immune System Process Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Regulation Of Macromolecule Metabolic Process Neurotrophin TRKA Receptor Binding Regulation Of MRNA Metabolic Process Regulation Of Caveolin-mediated Endocytosis Osteoclast Development Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Developmental Process Regulation Of Immune System Process Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Signal Complex Assembly T Cell Costimulation	WW Domain Binding Spermine Transmembrane Transport ABC-type Polyamine Transporter Activity Microtubule Nucleation By Interphase Microtubule Organizing Center
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