IFT25 and SEC23IP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		IFT25	SEC23IP
Description		intraflagellar transport 25	SEC23 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Cell Projection Ciliary Tip	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding Metal Ion Binding	RNA Binding Phospholipase Activity Protein Binding Metal Ion Binding
	Biological Process	Skeletal System Development Kidney Development Smoothened Signaling Pathway Spermatogenesis Heart Development Protein Transport Cell Differentiation Lung Development Intraciliary Anterograde Transport Intraciliary Transport Cilium Assembly Left/right Axis Specification	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Endomembrane System Organization
Pathways		Intraflagellar transport Intraflagellar transport	COPII-mediated vesicle transport
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS			Appendicular lean mass ( 33097823) Cerebrospinal fluid clusterin levels ( 26545630) HDL cholesterol levels ( 32203549) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870)
Interacting Genes		5 interacting genes: GORASP2 IFT27 NUP62 SEC23IP TRAF3	10 interacting genes: BTG3 DSCR9 IFT25 PCNA POLD4 RNF10 SEC23A SSC5D WWOX YIF1A
Entrez ID		51668	11196
HPRD ID		12730	07152
Ensembl ID		ENSG00000081870	ENSG00000107651
Uniprot IDs		Q9Y547 X6R7Y7	A0A994J542 Q9Y6Y8
PDB IDs		1TVG 1XPW
Enriched GO Terms of Interacting Partners?		Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization Golgi Organization Organelle Assembly Toll Signaling Pathway Organelle Organization Endomembrane System Organization PTB Domain Binding Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Protein Transport	Mesenchymal Cell Differentiation Involved In Lung Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow Mammary Gland Bud Formation Fibroblast Growth Factor Receptor Signaling Pathway Involved In Hemopoiesis Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Branch Elongation Involved In Salivary Gland Morphogenesis Response To Transforming Growth Factor Beta Cellular Response To Transforming Growth Factor Beta Stimulus PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity DNA Synthesis Involved In DNA Repair Purine-specific Mismatch Base Pair DNA N-glycosylase Activity COPII-coated ER To Golgi Transport Vesicle Ventricular Zone Neuroblast Division Prostate Epithelial Cord Elongation Prostate Gland Morphogenesis Mesenchymal Cell Proliferation Involved In Lung Development Fibroblast Growth Factor Receptor Activity Orbitofrontal Cortex Development Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Lung Development Skeletal System Morphogenesis Positive Regulation Of Phospholipase Activity Forebrain Neuroblast Division DNA Biosynthetic Process Positive Regulation Of Deoxyribonuclease Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Leading Strand Elongation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane COPII-coated Vesicle Budding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Delta DNA Polymerase Complex Detection Of Bacterial Lipoprotein
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