SEC23IP and IFT25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SEC23IP	IFT25
Description		SEC23 interacting protein	intraflagellar transport 25
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle	Centrosome Cilium Intraciliary Transport Particle B Cell Projection Ciliary Tip
	Molecular Function	RNA Binding Phospholipase Activity Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Endomembrane System Organization	Skeletal System Development Kidney Development Smoothened Signaling Pathway Spermatogenesis Heart Development Protein Transport Cell Differentiation Lung Development Intraciliary Anterograde Transport Intraciliary Transport Cilium Assembly Left/right Axis Specification
Pathways		COPII-mediated vesicle transport	Intraflagellar transport Intraflagellar transport
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Appendicular lean mass ( 33097823) Cerebrospinal fluid clusterin levels ( 26545630) HDL cholesterol levels ( 32203549) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870)
Interacting Genes		10 interacting genes: BTG3 DSCR9 IFT25 PCNA POLD4 RNF10 SEC23A SSC5D WWOX YIF1A	5 interacting genes: GORASP2 IFT27 NUP62 SEC23IP TRAF3
Entrez ID		11196	51668
HPRD ID		07152	12730
Ensembl ID		ENSG00000107651	ENSG00000081870
Uniprot IDs		A0A994J542 Q9Y6Y8	Q9Y547 X6R7Y7
PDB IDs			1TVG 1XPW
Enriched GO Terms of Interacting Partners?		Mesenchymal Cell Differentiation Involved In Lung Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow Mammary Gland Bud Formation Fibroblast Growth Factor Receptor Signaling Pathway Involved In Hemopoiesis Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Branch Elongation Involved In Salivary Gland Morphogenesis Response To Transforming Growth Factor Beta Cellular Response To Transforming Growth Factor Beta Stimulus PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity DNA Synthesis Involved In DNA Repair Purine-specific Mismatch Base Pair DNA N-glycosylase Activity COPII-coated ER To Golgi Transport Vesicle Ventricular Zone Neuroblast Division Prostate Epithelial Cord Elongation Prostate Gland Morphogenesis Mesenchymal Cell Proliferation Involved In Lung Development Fibroblast Growth Factor Receptor Activity Orbitofrontal Cortex Development Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Lung Development Skeletal System Morphogenesis Positive Regulation Of Phospholipase Activity Forebrain Neuroblast Division DNA Biosynthetic Process Positive Regulation Of Deoxyribonuclease Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Leading Strand Elongation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane COPII-coated Vesicle Budding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Delta DNA Polymerase Complex Detection Of Bacterial Lipoprotein	Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization Golgi Organization Organelle Assembly Toll Signaling Pathway Organelle Organization Endomembrane System Organization PTB Domain Binding Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Protein Transport
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