SEC23IP and SSC5D

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SEC23IP	SSC5D
Description		SEC23 interacting protein	scavenger receptor cysteine rich family member with 5 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Membrane COPII-coated ER To Golgi Transport Vesicle Cytoplasmic Vesicle	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Matrix
	Molecular Function	RNA Binding Phospholipase Activity Protein Binding Metal Ion Binding	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Endomembrane System Organization	Immune System Process Defense Response Vesicle-mediated Transport Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		COPII-mediated vesicle transport	Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Cerebrospinal fluid clusterin levels ( 26545630) HDL cholesterol levels ( 32203549) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		10 interacting genes: BTG3 DSCR9 IFT25 PCNA POLD4 RNF10 SEC23A SSC5D WWOX YIF1A	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		11196	284297
HPRD ID		07152	11444
Ensembl ID		ENSG00000107651	ENSG00000179954
Uniprot IDs		A0A994J542 Q9Y6Y8	A1L4H1
PDB IDs
Enriched GO Terms of Interacting Partners?		Mesenchymal Cell Differentiation Involved In Lung Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow Mammary Gland Bud Formation Fibroblast Growth Factor Receptor Signaling Pathway Involved In Hemopoiesis Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Branch Elongation Involved In Salivary Gland Morphogenesis Response To Transforming Growth Factor Beta Cellular Response To Transforming Growth Factor Beta Stimulus PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity DNA Synthesis Involved In DNA Repair Purine-specific Mismatch Base Pair DNA N-glycosylase Activity COPII-coated ER To Golgi Transport Vesicle Ventricular Zone Neuroblast Division Prostate Epithelial Cord Elongation Prostate Gland Morphogenesis Mesenchymal Cell Proliferation Involved In Lung Development Fibroblast Growth Factor Receptor Activity Orbitofrontal Cortex Development Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Lung Development Skeletal System Morphogenesis Positive Regulation Of Phospholipase Activity Forebrain Neuroblast Division DNA Biosynthetic Process Positive Regulation Of Deoxyribonuclease Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Leading Strand Elongation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane COPII-coated Vesicle Budding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Delta DNA Polymerase Complex Detection Of Bacterial Lipoprotein	Regulation Of DNA-templated Transcription Elongation Core Mediator Complex Cytoskeleton Organization Cellular Component Assembly RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Receptor Internalization Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Mitotic Cytokinesis Organelle Localization Regulation Of Cytokinesis Microtubule-based Process Regulation Of Mitotic Cytokinesis BLOC-1 Complex Negative Regulation Of Receptor Internalization Regulation Of Transcription Elongation By RNA Polymerase II Mitotic Spindle Microtubule Anterograde Synaptic Vesicle Transport Regulation Of Mitotic Nuclear Division Regulation Of Receptor-mediated Endocytosis Organelle Organization Transcription Coregulator Activity Platelet Dense Granule Organization Centrosome Regulation Of Nuclear Division Negative Regulation Of Receptor-mediated Endocytosis Flemming Body Regulation Of Microtubule Cytoskeleton Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Regulation Of Cell Division Midbody Protein-DNA Complex Assembly Positive Regulation Of Cytokinesis Microtubule Cytoskeleton Organization Anterograde Axonal Transport Cis-trans Isomerase Activity Interleukin-5 Receptor Complex Positive Regulation Of Mitotic Nuclear Division Mitotic Metaphase Chromosome Alignment Vesicle Transport Along Microtubule Establishment Of Protein Localization
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