DYNC2LI1 and CLIP4

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		DYNC2LI1	CLIP4
Description		dynein cytoplasmic 2 light intermediate chain 1	CAP-Gly domain containing linker protein family member 4
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Cilium Axoneme Nuclear Speck Dynein Complex Motile Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Apical Part Of Cell Ciliary Tip	Nucleus Cell Cortex Microtubule Plus-end
	Molecular Function	Protein Binding Dynein Heavy Chain Binding	Protein Binding Microtubule Plus-end Binding
	Biological Process	Determination Of Left/right Symmetry Cell Projection Organization Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Cilium Assembly Regulation Of Cilium Assembly	Cytoplasmic Microtubule Organization
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hematocrit ( 32888494) Hemoglobin ( 32888494) Red blood cell count ( 32888494) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: CLIP4 DCDC2 DYNC2H1	37 interacting genes: APP CDK5RAP2 CLIP1 CMYA5 DCAF6 DES DST DYNC2LI1 GLP1R HSF2BP JAKMIP2 KIF1B KIFC3 LZTS2 MAGEA12 MAP7 MAP7D1 MEOX2 MYBPC1 MYH3 PDE4DIP PEG10 RPS13 RPS27L RUNX1 SIX2 SON TACC3 TAF1 TNNT1 TNNT3 TPM1 TRIM32 TRIP13 TTN TULP3 ZNF114
Entrez ID		51626	79745
HPRD ID		13116	08634
Ensembl ID		ENSG00000138036	ENSG00000115295
Uniprot IDs		Q8TCX1	A0A8I5KXU9 A0A8I5QKP4 A0A8I5QKV0 A8K6D0 B7Z936 G3XAK3 Q8N3C7
PDB IDs		6RLB 6SC2 8RGH	2Z0W
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Smoothened Signaling Pathway Kinase Binding Regulation Of Smoothened Signaling Pathway Axoneme	Cytoskeleton Organization Sarcomere Organization Organelle Organization Microtubule-based Process Microtubule Cytoskeleton Organization Actomyosin Structure Organization Microtubule Skeletal Muscle Contraction Striated Muscle Contraction Microtubule Binding Muscle Filament Sliding Muscle Contraction Actin-myosin Filament Sliding Centrosome Actin Cytoskeleton Organization Cytoskeleton Microtubule Plus-end Microtubule Cytoskeleton Muscle System Process M Band Actin Filament-based Process Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Microtubule Polymerization Actin-mediated Cell Contraction Female Meiosis I Structural Constituent Of Muscle Troponin Complex Myofibril Male Meiotic Nuclear Division Regulation Of Supramolecular Fiber Organization Actin Filament-based Movement Contractile Muscle Fiber Tropomyosin Binding Regulation Of Microtubule Polymerization Cytoskeletal Protein Binding Regulation Of Microtubule Cytoskeleton Organization Transport Along Microtubule Meiotic Nuclear Division Female Meiotic Nuclear Division Axo-dendritic Transport Positive Regulation Of Cytoskeleton Organization Supramolecular Fiber Organization Retrograde Axonal Transport Microtubule Plus-end Binding Positive Regulation Of Protein Polymerization Cytoskeleton-dependent Intracellular Transport Myosin Filament Nuclear Division Regulation Of Cytoskeleton Organization Amyloid-beta Complex
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