LSR and MAPKAPK5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LSR	MAPKAPK5
Gene Name		lipolysis stimulated lipoprotein receptor	mitogen-activated protein kinase-activated protein kinase 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Chylomicron Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm
	Molecular Function		P53 Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Liver Development Regulation Of Lipid Metabolic Process	MAPK Cascade Activation Of MAPK Activity Regulation Of Translation Signal Transduction Ras Protein Signal Transduction Negative Regulation Of TOR Signaling Protein Autophosphorylation Stress-induced Premature Senescence
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MAPKAPK5 RARG YWHAG	28 interactors: ATF2 CDCA8 EEF2K EIF4E EIF4EBP1 GYS1 HSPB1 HSPB2 JUN LSR MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK4 MAPK6 MAPK9 MBP MYH11 PLA2G4A RPL13 SRPK1 SRPK2 TAB1 TP53 ZNF282 ZNF576
Entrez ID		51599	8550
HPRD ID		17283	09467
Ensembl ID		ENSG00000105699	ENSG00000089022
Uniprot IDs		B4DKL4 Q86X29	Q8IW41
PDB IDs
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Growth Plate Cartilage Chondrocyte Differentiation Retinal Pigment Epithelium Development Lacrimal Gland Development Stress-induced Premature Senescence Chondrocyte Development Involved In Endochondral Bone Morphogenesis Trachea Cartilage Development Cellular Response To Hormone Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Growth Plate Cartilage Development Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Negative Regulation Of Chondrocyte Differentiation Regulation Of Kinase Activity Retinoic Acid Receptor Signaling Pathway Endochondral Bone Growth Glandular Epithelial Cell Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Trachea Development Cellular Senescence Negative Regulation Of Cartilage Development Chondrocyte Development Negative Regulation Of TOR Signaling Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cartilage Development Involved In Endochondral Bone Morphogenesis Response To Hormone Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Embryonic Eye Morphogenesis Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Regulation Of Protein Phosphorylation Regulation Of Myelination Embryonic Hindlimb Morphogenesis Face Development Exocrine System Development Positive Regulation Of Mitochondrion Organization Embryonic Camera-type Eye Development Hindlimb Morphogenesis Regulation Of TOR Signaling Positive Regulation Of Signal Transduction Cellular Response To Retinoic Acid Prostate Gland Development Regulation Of Chondrocyte Differentiation	MAPK Cascade Signal Transduction By Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Intracellular Signal Transduction Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Phosphorylation Regulation Of Innate Immune Response Response To Organic Substance Response To Stress Gene Expression Cellular Response To Organic Substance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Protein Phosphorylation Signaling Phosphate-containing Compound Metabolic Process Cell Cycle Cell Communication Ras Protein Signal Transduction Innate Immune Response Signal Transduction Mitochondrion Organization Regulation Of Cellular Protein Metabolic Process Immune Response-regulating Signaling Pathway Apoptotic Mitochondrial Changes Defense Response Response To Toxic Substance Cellular Response To Stimulus Response To Stimulus
Tagcloud ?		111in accumulation arthus bgg challenge cycloheximide giving globulin haemorrhage immediately injection injections intradermal labelled leakage local lps microgram micrograms neutrophil oedema p55 passive priming rabbit rhtnf rpa sf2 shwartzman	acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Difference) ?		111in accumulation arthus bgg challenge cycloheximide giving globulin haemorrhage immediately injection injections intradermal labelled leakage local lps microgram micrograms neutrophil oedema p55 passive priming rabbit rhtnf rpa sf2 shwartzman	acids amino blot designated encodes erk gst homology identities jnk jun kinase light mitogen myosin northern novel nucleotide p38 phosphorylate phosphorylated recombinant sequence shares substrate wide
Tagcloud (Intersection) ?