LSR and RARG

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LSR	RARG
Gene Name		lipolysis stimulated lipoprotein receptor	retinoic acid receptor, gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Very-low-density Lipoprotein Particle Low-density Lipoprotein Particle Chylomicron Extracellular Vesicular Exosome	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Integral Component Of Membrane
	Molecular Function		RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding Retinoid X Receptor Binding
	Biological Process	Liver Development Regulation Of Lipid Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neural Tube Closure Glandular Epithelial Cell Development Retinal Pigment Epithelium Development Growth Plate Cartilage Chondrocyte Growth Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Regulation Of Cell Size Anterior/posterior Pattern Specification Gene Expression Embryonic Camera-type Eye Development Regulation Of Myelination Negative Regulation Of Chondrocyte Differentiation Response To Retinoic Acid Embryonic Hindlimb Morphogenesis Multicellular Organism Growth Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Eye Morphogenesis Retinoic Acid Receptor Signaling Pathway Transmembrane Transport Canonical Wnt Signaling Pathway Face Development Trachea Cartilage Development Prostate Gland Epithelium Morphogenesis Harderian Gland Development Cellular Response To Retinoic Acid
Pathways			Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters
Drugs			Adapalene Acitretin Alitretinoin Tretinoin Tazarotene Etretinate SR11254 4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid CD564 Dodecyl-Alpha-D-Maltoside BMS184394 R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MAPKAPK5 RARG YWHAG	29 interactors: ACY3 EIF3I HMGA1 IL24 ITGB1BP2 LSR MAP6 MRPL12 MTMR6 NCOA1 NCOA3 NCOR1 NCOR2 NKX3-1 NR0B2 NR2F6 OIP5 PNRC1 PNRC2 RHPN2 RXRA RXRB RXRG SMAD3 SPHK1 SRC SRF TNIP1 ZNF576
Entrez ID		51599	5916
HPRD ID		17283	01573
Ensembl ID		ENSG00000105699	ENSG00000172819
Uniprot IDs		B4DKL4 Q86X29	A8K3H3 B7Z4B4 F1D8P1 P13631
PDB IDs			1EXA 1EXX 1FCX 1FCY 1FCZ 1FD0 2LBD 3LBD 4LBD
Enriched GO Terms of Interacting Partners?		Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Growth Plate Cartilage Chondrocyte Differentiation Retinal Pigment Epithelium Development Lacrimal Gland Development Stress-induced Premature Senescence Chondrocyte Development Involved In Endochondral Bone Morphogenesis Trachea Cartilage Development Cellular Response To Hormone Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Growth Plate Cartilage Development Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Protein Kinase Activity Negative Regulation Of Chondrocyte Differentiation Regulation Of Kinase Activity Retinoic Acid Receptor Signaling Pathway Endochondral Bone Growth Glandular Epithelial Cell Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Trachea Development Cellular Senescence Negative Regulation Of Cartilage Development Chondrocyte Development Negative Regulation Of TOR Signaling Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cartilage Development Involved In Endochondral Bone Morphogenesis Response To Hormone Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Embryonic Eye Morphogenesis Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Regulation Of Protein Phosphorylation Regulation Of Myelination Embryonic Hindlimb Morphogenesis Face Development Exocrine System Development Positive Regulation Of Mitochondrion Organization Embryonic Camera-type Eye Development Hindlimb Morphogenesis Regulation Of TOR Signaling Positive Regulation Of Signal Transduction Cellular Response To Retinoic Acid Prostate Gland Development Regulation Of Chondrocyte Differentiation	Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Transcription, DNA-templated Response To Steroid Hormone Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process DNA-templated Transcription, Initiation Response To Hormone Gene Expression Cellular Response To Organic Substance Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Response To Steroid Hormone Stimulus Response To Lipid Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Steroid Hormone Mediated Signaling Pathway Regulation Of RNA Biosynthetic Process Response To Organic Cyclic Compound Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Hormone-mediated Signaling Pathway RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Response To Organic Cyclic Compound Cellular Response To Hormone Stimulus Cellular Response To Lipid Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gland Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Organ Development System Development Intracellular Steroid Hormone Receptor Signaling Pathway In Utero Embryonic Development Heart Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Nucleobase-containing Compound Metabolic Process Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Transcription, DNA-templated Cellular Response To Stimulus Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		111in accumulation arthus bgg challenge cycloheximide giving globulin haemorrhage immediately injection injections intradermal labelled leakage local lps microgram micrograms neutrophil oedema p55 passive priming rabbit rhtnf rpa sf2 shwartzman	activating backcross chromosomes contain cosegregated enhancers fragment homology interspecific loci mapped mchr mediate none rara rarb reports responsive restriction retinoic retinoid rflvs rxr subclass syntenic terms trans variants
Tagcloud (Difference) ?		111in accumulation arthus bgg challenge cycloheximide giving globulin haemorrhage immediately injection injections intradermal labelled leakage local lps microgram micrograms neutrophil oedema p55 passive priming rabbit rhtnf rpa sf2 shwartzman	activating backcross chromosomes contain cosegregated enhancers fragment homology interspecific loci mapped mchr mediate none rara rarb reports responsive restriction retinoic retinoid rflvs rxr subclass syntenic terms trans variants
Tagcloud (Intersection) ?