TRMO and RAD54B

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		TRMO	RAD54B
Description		tRNA methyltransferase O	RAD54 homolog B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity TRNA (L-threonylcarbamoyladenosine(37)-C2) Methyltransferase Activity	Nucleotide Binding DNA Binding DNA Helicase Activity RNA Helicase Activity Helicase Activity Protein Binding ATP Binding DNA Translocase Activity Hydrolase Activity
	Biological Process	TRNA Processing TRNA Methylation Methylation	Double-strand Break Repair Via Homologous Recombination DNA Repair Mitotic Recombination DNA Damage Response Reciprocal Meiotic Recombination Determination Of Adult Lifespan Response To Xenobiotic Stimulus Response To Ionizing Radiation
Pathways
Drugs
Diseases
GWAS		Orofacial clefts ( 33137956)	Age at first sexual intercourse ( 34211149) Nonsyndromic cleft lip with cleft palate ( 28232668)
Interacting Genes		22 interacting genes: AURKA BCL10 BMPR1A BUB1 CCND1 DCC DLC1 EGFR ERBB2 MCC MLH1 NRAS PMS2 PTEN PTPRJ RAD54B RB1 SMAD2 SPATC1L STAC STK11 TGFBR2	30 interacting genes: ANKRD36BP1 ATPAF2 BAAT CCDC33 CDC23 CSNK1E DMC1 DYRK2 ELOA ENKD1 GMCL1 GORASP2 IGFBP3 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SFRP2 SUMO1 TCEANC TRAPPC6A TRMO UBE2I WRN ZNF580
Entrez ID		51531	25788
HPRD ID		12945	05049
Ensembl ID		ENSG00000136932	ENSG00000197275
Uniprot IDs		Q5T114 Q9BU70	Q9Y620
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Epithelial Cell Proliferation Intracellular Signal Transduction Regulation Of Multicellular Organismal Process Protein Kinase Activity Regulation Of Cell Population Proliferation Signal Transduction Regulation Of Growth Kinase Activity Heart Valve Morphogenesis Regulation Of Phosphorylation Regulation Of Cell Differentiation Heart Development Negative Regulation Of Developmental Process Negative Regulation Of Cell Differentiation Regulation Of Developmental Process Regulation Of Cell Communication Regulation Of Signaling Cell Population Proliferation Regulation Of Signal Transduction Endocardial Cushion Morphogenesis Nucleotide Binding Epithelial Cell Proliferation Regulation Of Mitotic Cell Cycle Phase Transition ATP Binding Positive Regulation Of Epithelial Cell Proliferation Regulation Of Cell Development Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process MutLalpha Complex Intracellular Signaling Cassette Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Phosphorylation Ruffle Membrane Negative Regulation Of Growth Apoptotic Process Regulation Of Cell Growth Tricuspid Valve Morphogenesis Cell Surface Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Programmed Cell Death Cytosol Cell Death Aortic Valve Morphogenesis Regulation Of Cell Cycle Phase Transition Mismatch Repair Complex Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Cycle Process	DNA Strand Exchange Activity DNA Strand Invasion DNA Recombinase Assembly Small Protein Activating Enzyme Binding Catalytic Activity, Acting On DNA Response To Ionizing Radiation Response To Gamma Radiation Double-strand Break Repair Involved In Meiotic Recombination Cellular Response To Stress Lateral Element Cellular Response To Ionizing Radiation DNA Damage Response ATP-dependent DNA Damage Sensor Activity
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