TRMO

Description		tRNA methyltransferase O
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity TRNA (L-threonylcarbamoyladenosine(37)-C2) Methyltransferase Activity
	Biological Process	TRNA Processing TRNA Methylation Methylation
Pathways
Drugs
Diseases
GWAS		Orofacial clefts ( 33137956)
Interacting Genes		22 interacting genes: AURKA BCL10 BMPR1A BUB1 CCND1 DCC DLC1 EGFR ERBB2 MCC MLH1 NRAS PMS2 PTEN PTPRJ RAD54B RB1 SMAD2 SPATC1L STAC STK11 TGFBR2
Entrez ID		51531
HPRD ID		12945
Ensembl ID		ENSG00000136932
Uniprot IDs		Q5T114 Q9BU70
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Epithelial Cell Proliferation Intracellular Signal Transduction Regulation Of Multicellular Organismal Process Protein Kinase Activity Regulation Of Cell Population Proliferation Signal Transduction Regulation Of Growth Kinase Activity Heart Valve Morphogenesis Regulation Of Phosphorylation Regulation Of Cell Differentiation Heart Development Negative Regulation Of Developmental Process Negative Regulation Of Cell Differentiation Regulation Of Developmental Process Regulation Of Cell Communication Regulation Of Signaling Cell Population Proliferation Regulation Of Signal Transduction Endocardial Cushion Morphogenesis Nucleotide Binding Epithelial Cell Proliferation Regulation Of Mitotic Cell Cycle Phase Transition ATP Binding Positive Regulation Of Epithelial Cell Proliferation Regulation Of Cell Development Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process MutLalpha Complex Intracellular Signaling Cassette Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Phosphorylation Ruffle Membrane Negative Regulation Of Growth Apoptotic Process Regulation Of Cell Growth Tricuspid Valve Morphogenesis Cell Surface Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Programmed Cell Death Cytosol Cell Death Aortic Valve Morphogenesis Regulation Of Cell Cycle Phase Transition Mismatch Repair Complex Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Cycle Process
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