VCX2 and STAC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VCX2	STAC3
Description		variable charge X-linked 2	SH3 and cysteine rich domain 3
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane T-tubule Sarcolemma Synapse
	Molecular Function		Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Brain Development	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS			Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Glycated hemoglobin levels ( 34059833) Schizophrenia ( 25056061 29483656)
Interacting Genes		9 interacting genes: BEND7 DDIT4L GSC2 MACROH2A1 MEOX2 PAX6 STAC3 THAP1 ZNF526	38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A DRC4 EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT
Entrez ID		51480	246329
HPRD ID		06749	11606
Ensembl ID		ENSG00000177504	ENSG00000185482
Uniprot IDs		Q9H322	Q96MF2
PDB IDs			2DB6 6B29 6UY7 6UY8 6UY9
Enriched GO Terms of Interacting Partners?		DNA Binding Sequence-specific DNA Binding Chromatin DNA-binding Transcription Factor Activity Forebrain-midbrain Boundary Formation Positive Regulation Of Epithelial Cell Differentiation Pancreatic A Cell Development Negative Regulation Of Protein Localization To Chromosome, Telomeric Region RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA Binding ADP-D-ribose Binding Regulation Of NAD Metabolic Process Regulation Of RDNA Heterochromatin Formation DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Habenula Development Pallium Development Positive Regulation Of Endodermal Cell Differentiation Positive Regulation Of Response To Oxidative Stress ADP-D-ribose Modification-dependent Protein Binding Sequence-specific Double-stranded DNA Binding Somite Specification Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification Formation Of Anatomical Boundary Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Regulation Of Epithelial Cell Differentiation Telencephalon Regionalization Poly-ADP-D-ribose Modification-dependent Protein Binding RDNA Binding Sex Chromatin Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Double-stranded Methylated DNA Binding Barr Body Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Transcription By RNA Polymerase II Type B Pancreatic Cell Differentiation Forebrain Neuron Fate Commitment Ventral Spinal Cord Development Iris Morphogenesis Negative Regulation Of Response To Oxidative Stress Establishment Of Protein Localization To Chromatin Regulation Of Heterochromatin Formation Cornea Development In Camera-type Eye Salivary Gland Morphogenesis Negative Regulation Of Transcription By RNA Polymerase I	Transcription Elongation Factor Complex Super Elongation Complex Transcription Elongation By RNA Polymerase II Transcription Elongation Factor Activity DNA-templated Transcription Elongation Transcription Regulator Activator Activity
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