MBTPS2 and ATF6B

Number of citations of the paper that reports this interaction (PMID 11163209)
293

Data Source:
HPRD (in vivo)

		MBTPS2	ATF6B
Gene Name		membrane-bound transcription factor peptidase, site 2	activating transcription factor 6 beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Integral Component Of Membrane	Intracellular Nucleus Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-DNA Complex
	Molecular Function	Metalloendopeptidase Activity Metal Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress	Transcription, DNA-templated Signal Transduction Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Metabolism of lipids and lipoproteins ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23577725) Prostate cancer ( 23535732)
Protein-Protein Interactions		1 interactors: ATF6B	9 interactors: ATF6 CDK6 CREBZF MBTPS1 MBTPS2 NFYA NFYC PHOX2A XBP1
Entrez ID		51360	1388
HPRD ID		02243	02992
Ensembl ID		ENSG00000012174	ENSG00000213676
Uniprot IDs		O43462	Q6AZW6 Q99941
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Response To Endoplasmic Reticulum Stress	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Positive Regulation Of Gene Expression Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Kinase Activity Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of Kinase Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Transcription, DNA-templated RNA Biosynthetic Process Membrane Protein Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of RNA Biosynthetic Process Positive Regulation Of Phosphorylation Regulation Of DNA-templated Transcription In Response To Stress Regulation Of RNA Metabolic Process Positive Regulation Of Protein Modification Process RNA Metabolic Process Positive Regulation Of Hydrolase Activity Positive Regulation Of Lactation Locus Ceruleus Development Cell Dedifferentiation Trochlear Nerve Formation Positive Regulation Of Plasma Cell Differentiation Serotonin Secretion, Neurotransmission Epithelial Cell Maturation Involved In Salivary Gland Development
Tagcloud ?		adaptation anterior atf4 bip carbohydrates chop consuming disrupt fat flexors inducers ire1alpha mtorc1 muscles myogenic overload palmitic plantar s6k1 soleus spliced thapsigargin tibialis tunicamycin unfolded unspliced upr wk xbp1
Tagcloud (Difference) ?		adaptation anterior atf4 bip carbohydrates chop consuming disrupt fat flexors inducers ire1alpha mtorc1 muscles myogenic overload palmitic plantar s6k1 soleus spliced thapsigargin tibialis tunicamycin unfolded unspliced upr wk xbp1
Tagcloud (Intersection) ?