MBTPS2

Gene Name		membrane-bound transcription factor peptidase, site 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Cellular Protein Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Metabolism of lipids and lipoproteins ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: ATF6B
Entrez ID		51360
HPRD ID		02243
Ensembl ID		ENSG00000012174
Uniprot IDs		O43462
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Response To Endoplasmic Reticulum Stress
Tagcloud ?		adaptation anterior atf4 bip carbohydrates chop consuming disrupt fat flexors inducers ire1alpha mtorc1 muscles myogenic overload palmitic plantar s6k1 soleus spliced thapsigargin tibialis tunicamycin unfolded unspliced upr wk xbp1