DACT1 and C7orf25

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DACT1	C7orf25
Gene Name		dishevelled-binding antagonist of beta-catenin 1	chromosome 7 open reading frame 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cell Junction Beta-catenin Destruction Complex Synapse
	Molecular Function	Protein Kinase C Binding Protein Binding Beta-catenin Binding Protein Kinase A Binding Delta-catenin Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Gastrulation With Mouth Forming Second Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Stability Regulation Of Catenin Import Into Nucleus Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Protein Catabolic Process Negative Regulation Of JNK Cascade Embryonic Hindgut Morphogenesis Dendrite Morphogenesis Synapse Organization Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Nodal Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN degradation of DVL Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: C7orf25 CSNK2B PPP1CC SH3GL2 TK1	18 interactors: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 HAP1 HEXDC MTOR NGEF PTN RASSF1 RPL36AL SF3B2 TARS UBE2D1
Entrez ID		51339	79020
HPRD ID		09709	09861
Ensembl ID		ENSG00000165617	ENSG00000136197
Uniprot IDs		Q9NYF0	Q9BPX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Response To Organic Substance Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Thymidine Metabolic Process Response To Cortisol Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Axon Guidance Endothelial Tube Morphogenesis Cellular Response To Organic Substance Axonogenesis Parturition Negative Regulation Of Blood Vessel Endothelial Cell Migration Axon Development Cellular Response To Growth Factor Stimulus Triglyceride Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Response To Growth Factor Entrainment Of Circadian Clock By Photoperiod Regulation Of Activin Receptor Signaling Pathway Response To Copper Ion Neuron Projection Morphogenesis Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Tube Development Regulation Of Receptor Internalization Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle Regulation Of Signal Transduction Negative Regulation Of Endothelial Cell Migration Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Pyrimidine Nucleobase Metabolic Process Phosphate-containing Compound Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cell Part Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Signaling Negative Regulation Of Epithelial Cell Migration Negative Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway	Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Stress Regulation Of Intracellular Signal Transduction Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Protein Catabolic Process Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Differentiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Cell Projection Organization Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Protein Modification Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Differentiation Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Division Positive Regulation Of Neurotrophin Production Regulation Of Carbohydrate Utilization Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		associations blotting ccnd1 ccnd2 dab2 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Difference) ?		associations blotting ccnd1 ccnd2 dab2 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Intersection) ?