SRSF11 and PUF60

Number of citations of the paper that reports this interaction (PMID 10606266)
31

Data Source:
HPRD (in vitro)

		SRSF11	PUF60
Gene Name		serine/arginine-rich splicing factor 11	poly-U binding splicing factor 60KDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Mitochondrion Golgi Apparatus Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding DNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Apoptotic Process RNA Splicing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ARL6IP4 CDK6 CSNK2A1 DDOST ETS1 GATC HYI MDM2 PIN1 PUF60 RBM39 RNPS1 SDCBP SREK1 SRSF1 SRSF2 TANK THAP11 TOP1 U2AF2	30 interactors: ARL8A CACNA1A CCNC CD101 CHD3 ERG FHL2 FUBP1 HIST1H1C ID3 KIAA0907 KIAA1683 LOH12CR1 MED28 PCBP1 PPP1R16A PTBP2 QRICH1 RAD23B SAP30BP SDCBP SIAH1 SNRPF SRSF11 U2AF2 UBE2I UPF2 VIM YWHAG ZG16
Entrez ID		9295	22827
HPRD ID		03599	18051
Ensembl ID		ENSG00000116754	ENSG00000179950
Uniprot IDs		Q05519 Q5T757	Q9UHX1
PDB IDs			2DNY 2KXF 2KXH 2QFJ 3DXB 3UE2 3US5 3UWT
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Gene Expression DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing RNA Metabolic Process RNA 3'-end Processing Nuclear Export MRNA Transport RNA Transport Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Localization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transcription, DNA-templated Regulation Of MRNA Processing RNA Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Biosynthetic Process Cellular Metabolic Process Regulation Of Gene Expression Negative Regulation Of RNA Splicing Cytoplasmic Transport Regulation Of Erythrocyte Differentiation Negative Regulation Of Cell Cycle Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Cell Dedifferentiation Cellular Response To UV-C Cellular Response To Vitamin B1 Cellular Response To Hydrogen Peroxide Intracellular Transport Response To Antibiotic Regulation Of RNA Metabolic Process	RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing RNA 3'-end Processing Negative Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Nuclear Export MRNA Transport RNA Processing Regulation Of Metabolic Process RNA Transport RNA Localization Regulation Of Gene Expression Membrane Depolarization During Action Potential Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Death Negative Regulation Of Muscle Cell Differentiation Cerebellar Molecular Layer Development Negative Regulation Of Potassium Ion Export Positive Regulation Of SUMO Transferase Activity Vestibular Nucleus Development Nucleotide-excision Repair, DNA Damage Recognition Regulation Of Heart Rate By Hormone Negative Regulation Of Gene Expression Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Cerebellum Maturation Atrial Cardiac Muscle Cell Development Musculoskeletal Movement, Spinal Reflex Action Regulation Of Apoptotic Process
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter splice splicing u2 u2af65	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 splicing stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate jmjd6 localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter splice u2 u2af65	cadherin coding computational consisting decay downregulates enhancer fxr1 fxr2 hnrnp indicates lncrna lncrnas metastasis paired ranging remodelling ribonucleoprotein rnas rnp sf3b3 stimulates suppressing translation translational trerna upregulated utr
Tagcloud (Intersection) ?		splicing