ATP5D and EXOSC3

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		ATP5D	EXOSC3
Gene Name		ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	exosome component 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix	Nuclear Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleolus Cytoplasm Cytosol Transcriptionally Active Chromatin
	Molecular Function	Transporter Activity ATP Binding ATPase Activity Transmembrane Transporter Activity ADP Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	3'-5'-exoribonuclease Activity RNA Binding Exoribonuclease Activity Protein Binding
	Biological Process	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process Response To Copper Ion	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Gene Expression Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' U4 SnRNA 3'-end Processing Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay DNA Deamination Isotype Switching Positive Regulation Of Isotype Switching CUT Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process Nuclear Polyadenylation-dependent TRNA Catabolic Process Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription Polyadenylation-dependent SnoRNA 3'-end Processing
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling	Regulation of mRNA stability by proteins that bind AU-rich elements KSRP destabilizes mRNA mRNA decay by 3' to 5' exoribonuclease ATF4 activates genes Tristetraprolin (TTP) destabilizes mRNA PERK regulates gene expression Unfolded Protein Response (UPR) Deadenylation-dependent mRNA decay Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Drugs		Enflurane Isoflurane Methoxyflurane Halothane Desflurane Sevoflurane
Diseases
GWAS
Protein-Protein Interactions		1 interactors: EXOSC3	8 interactors: APP ATP5D CDK5RAP1 EXOSC4 EXOSC5 EXOSC8 EXOSC9 KHSRP
Entrez ID		513	51010
HPRD ID		04397	16220
Ensembl ID		ENSG00000099624	ENSG00000107371
Uniprot IDs		P30049	Q9NQT5 Q9NYS3
PDB IDs			2NN6
Enriched GO Terms of Interacting Partners?		Nuclear Polyadenylation-dependent TRNA Catabolic Process Polyadenylation-dependent SnoRNA 3'-end Processing Nuclear Retention Of Pre-mRNA With Aberrant 3'-ends At The Site Of Transcription U4 SnRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' TRNA Catabolic Process Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) SnoRNA Metabolic Process Nuclear MRNA Surveillance RRNA 3'-end Processing RNA Surveillance DNA Deamination Intracellular MRNA Localization RRNA Catabolic Process Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Isotype Switching Isotype Switching Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic SnRNA Processing RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Isotype Switching Somatic Recombination Of Immunoglobulin Gene Segments Positive Regulation Of Immunoglobulin Mediated Immune Response Somatic Diversification Of Immunoglobulins Positive Regulation Of Immunoglobulin Production SnRNA Metabolic Process Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Immunoglobulin Production Regulation Of DNA Recombination Positive Regulation Of B Cell Activation DNA Modification RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis RRNA Processing RRNA Metabolic Process Positive Regulation Of DNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process RNA Localization Positive Regulation Of Adaptive Immune Response Leukocyte Activation Involved In Immune Response B Cell Activation MRNA Catabolic Process Immunoglobulin Mediated Immune Response B Cell Mediated Immunity	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic MRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Catabolic Process MRNA Metabolic Process RRNA Processing RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Aromatic Compound Catabolic Process NcRNA Metabolic Process Ribosome Biogenesis Nuclear MRNA Surveillance Nucleobase-containing Compound Metabolic Process Ribonucleoprotein Complex Biogenesis DNA Deamination RNA Surveillance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Catabolic Process Cellular Nitrogen Compound Metabolic Process RNA Phosphodiester Bond Hydrolysis RNA Metabolic Process Nitrogen Compound Metabolic Process Catabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Gene Expression DNA Modification Synaptic Growth At Neuromuscular Junction Positive Regulation Of Cell Growth Regulation Of Growth Collateral Sprouting In Absence Of Injury Cellular Metabolic Process Defense Response To Virus Nuclear Polyadenylation-dependent RRNA Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Growth Neuron Remodeling Regulation Of MiRNA Metabolic Process Histone MRNA Catabolic Process Response To Virus Immune System Process RRNA Catabolic Process Regulation Of Cell Growth Mitochondrial ATP Synthesis Coupled Proton Transport Maturation Of 5.8S RRNA
Tagcloud ?		bear behaviors build cessation chronically clustering diethylamide drd2 gabrb1 hyperactivity illnesses krox20 lsd lysergic medial mpfc ndufa1 neurogenetic neuropeptide neurotransmission npy persist prefrontal qpcr schizophrenia seq sucrose underlie validate	aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b spag5 synapt tryptic unsupervised urgent
Tagcloud (Difference) ?		bear behaviors build cessation chronically clustering diethylamide drd2 gabrb1 hyperactivity illnesses krox20 lsd lysergic medial mpfc ndufa1 neurogenetic neuropeptide neurotransmission npy persist prefrontal qpcr schizophrenia seq sucrose underlie validate	aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b spag5 synapt tryptic unsupervised urgent
Tagcloud (Intersection) ?