SCAND1 and ZNF263

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		SCAND1	ZNF263
Description		SCAN domain containing 1	zinc finger protein 263
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Positive Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 25673412) Refractive error ( 32231278)
Interacting Genes		45 interacting genes: AGTRAP APH1A CALCOCO2 CCDC51 DGAT2L6 GOLGA6L9 GORASP2 KRT40 LHX4 MAPK3 MAPK8 MZF1 NDUFB5 NFE2 PICK1 PNMA1 POU2AF1 RER1 RNF186 RPRM SFT2D1 SHISA5 SLC17A9 TMEM207 TMEM239 TMEM95 TRIP6 TVP23A ZKSCAN3 ZKSCAN7 ZNF165 ZNF174 ZNF202 ZNF213 ZNF24 ZNF263 ZNF446 ZNF449 ZNF496 ZSCAN12 ZSCAN16 ZSCAN20 ZSCAN21 ZSCAN25 ZSCAN32	20 interacting genes: CLK2 CLK3 DVL2 EFEMP2 GPATCH2L JAKMIP2 LNX1 NME7 PCBD1 PLEKHF2 PPL SCAND1 SPG21 SUFU TCAF1 TRIM41 ZNF165 ZNF446 ZSCAN1 ZSCAN22
Entrez ID		51282	10127
HPRD ID		15298	05008
Ensembl ID		ENSG00000171222	ENSG00000006194
Uniprot IDs		P57086 Q9NZG6	D3DUC1 I3NI39 O14978
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Zinc Ion Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Xenophagy Sequence-specific DNA Binding Regulation Of Gene Expression MAP Kinase Activity Regulation Of Macromolecule Biosynthetic Process	Determination Of Bilateral Symmetry Determination Of Left/right Symmetry Regionalization
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