LUZP4 and CCDC6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LUZP4	CCDC6
Description		leucine zipper protein 4	coiled-coil domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Cytosol Cytoskeleton
	Molecular Function	RNA Binding Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	MRNA Transport	Cytoskeleton Organization
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases			Thyroid cancer
GWAS			Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		22 interacting genes: APPBP2 BACH2 CCDC6 CLK2 DDX39B DVL3 EMD FOS FOSL2 HSF2BP KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 LNX1 MORF4L2 NXF1 RCOR3 SRPK2 SRRM4 TLK1 TNS2	31 interacting genes: ATF2 ATF5 CCDC136 CCDC33 CREB1 CSNK2A1 CYTH4 DRC4 DSCR9 FBXW7 LHX3 LRSAM1 LUZP4 MAPK3 MAPK7 MEOX2 PAX6 PIN1 PPP4C SH3RF1 SNAPC1 SORBS3 TFIP11 TRIM14 UBE2I WAC ZNF250 ZNF354C ZNF620 ZNF774 ZNF835
Entrez ID		51213	8030
HPRD ID		06589	09064
Ensembl ID		ENSG00000102021	ENSG00000108091
Uniprot IDs		Q9P127	Q05CP8 Q16204
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Transcription Factor AP-1 Complex Intermediate Filament Transcription Export Complex Identical Protein Binding Nucleoplasm	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Nucleus Phosphothreonine Residue Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of DNA-templated Transcription Regulation Of Ubiquitin-dependent Protein Catabolic Process Pituitary Gland Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Macroautophagy Positive Regulation Of Macroautophagy Regulation Of Proteasomal Protein Catabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Catabolic Process MAPK Cascade Transcription Coregulator Binding Protein Stabilization Positive Regulation Of Xenophagy Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Gland Development Negative Regulation Of Proteolysis Signal Transduction In Response To DNA Damage DNA Binding CAMP Response Element Binding Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Autophagy MAP Kinase Activity Positive Regulation Of Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA Damage Response Positive Regulation Of Catabolic Process Positive Regulation Of Macromolecule Metabolic Process
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