ZDHHC2 and MAFB

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZDHHC2	MAFB
Gene Name		zinc finger, DHHC-type containing 2	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Integral Component Of Plasma Membrane Recycling Endosome Membrane	Nucleus Transcription Factor Complex
	Molecular Function	Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Protein Palmitoylation	Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development
Pathways
Drugs
Diseases
GWAS			Cholesterol, total ( 20686565) Dupuytren's disease ( 21732829) LDL cholesterol ( 19060906 20686565) Obesity-related traits ( 23251661) Response to TNF antagonist treatment ( 18615156)
Protein-Protein Interactions		2 interactors: MAFB MSX2	11 interactors: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT
Entrez ID		51201	9935
HPRD ID		15715	07129
Ensembl ID			ENSG00000204103
Uniprot IDs		Q9UIJ5	Q9Y5Q3
PDB IDs
Enriched GO Terms of Interacting Partners?		Rhombomere 6 Development Brain Segmentation Positive Regulation Of Mesenchymal Cell Apoptotic Process Negative Regulation Of CREB Transcription Factor Activity Positive Regulation Of Catagen Embryonic Nail Plate Morphogenesis Rhombomere 5 Development Activation Of Meiosis Frontal Suture Morphogenesis BMP Signaling Pathway Involved In Heart Development Pattern Specification Process Gland Development Negative Regulation Of Keratinocyte Differentiation Enamel Mineralization Nail Development Embryonic Morphogenesis Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Hair Follicle Development Tooth Mineralization Rhombomere Development Bone Trabecula Formation Negative Regulation Of Cell Differentiation Wound Healing, Spreading Of Epidermal Cells Cranial Suture Morphogenesis Outflow Tract Septum Morphogenesis Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Amelogenesis Negative Regulation Of Transcription Regulatory Region DNA Binding Craniofacial Suture Morphogenesis Segment Specification Regulation Of Hair Follicle Development Positive Regulation Of Meiotic Nuclear Division Endocardial Cushion Formation Bone Trabecula Morphogenesis Cellular Response To Estradiol Stimulus Organ Morphogenesis Regulation Of Hair Cycle Endocardial Cushion Morphogenesis Regulation Of Transcription Regulatory Region DNA Binding Cardiac Epithelial To Mesenchymal Transition Osteoblast Development Embryo Development Regulation Of Keratinocyte Differentiation Cellular Response To Estrogen Stimulus Endochondral Bone Growth Positive Regulation Of Epidermis Development Chondrocyte Development Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Epithelial Cell Differentiation	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cellular Macromolecule Biosynthetic Process Cellular Response To Extracellular Stimulus Regulation Of DNA-templated Transcription In Response To Stress Macromolecule Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Gravity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Response To CAMP Positive Regulation Of Gene Expression Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Learning Response To Organophosphorus Response To Extracellular Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Purine-containing Compound Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Response To Reactive Oxygen Species Response To Corticosterone Interaction With Symbiont Regulation Of Transcription, DNA-templated Response To Mechanical Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Mineralocorticoid Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Learning Or Memory Cellular Response To Calcium Ion Response To Progesterone Positive Regulation Of Myeloid Leukocyte Differentiation Toll-like Receptor 5 Signaling Pathway Cognition Toll-like Receptor 10 Signaling Pathway Regulation Of Gene Expression SMAD Protein Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?			aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1
Tagcloud (Difference) ?			aminobutyric bioassay catalase cip1 cyp7a1 den deoxyguanosine diethylnitrosamine doses drinking exhibits f344 foci gaba gst hepatocarcinogenesis hydroxy modulating nrf2 placental powerful ppm sitchensis suppress suppressing transferase valerian valeriana waf1
Tagcloud (Intersection) ?