ZNF639 and ZBTB24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF639	ZBTB24
Description		zinc finger protein 639	zinc finger and BTB domain containing 24
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Growth Host-mediated Suppression Of Viral Transcription Host-mediated Activation Of Viral Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Symbiont Entry Into Host Cell	Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Gout (normal type) ( 32238385) Response to antidepressants (symptom improvement) ( 29160301)	Depression in smokers ( 30219690) Height ( 18391951 20881960)
Interacting Genes		12 interacting genes: APTX CREBBP CRYAA MCRS1 MPP1 PNKP PRPF18 RIN3 ZBTB24 ZNF250 ZNF792 ZNF837	70 interacting genes: BACH2 BAX BCL11A BLZF1 CALM1 CCDC136 CCNDBP1 CDA CEP70 CEP76 DDHD1 DNM1L DVL3 FCHO1 GMCL1 GOLGA6L9 HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP5-9 LDOC1 LHX8 LNX1 LRRC18 MCIDAS MDFI MID2 NFE2L2 PDE4DIP PHC2 PICK1 POGZ POU6F2 PRMT7 RALY RBM10 RIN3 SPMIP2 SSX2IP SUV39H1 TLE5 TMEM121 TRAF2 TRIM37 TRIM41 TSC22D4 TSGA10 TSPYL2 ZBTB43 ZBTB8A ZBTB9 ZMYM6 ZNF526 ZNF639 ZNF79 ZNF792 ZNF837 ZRANB1
Entrez ID		51193	9841
HPRD ID		15882	18315
Ensembl ID		ENSG00000121864	ENSG00000112365
Uniprot IDs		Q9UID6	O43167
PDB IDs
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity Damaged DNA Binding Positive Regulation Of DNA Repair Histone Acetyltransferase Complex DNA Repair Regulation Of DNA Repair U2-type Post-spliceosomal Complex DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Negative Regulation Of Mast Cell Chemotaxis Positive Regulation Of DNA Metabolic Process Zinc Ion Binding DNA Metabolic Process Nucleus Histone H3K27 Acetyltransferase Activity Generation Of Catalytic Spliceosome For Second Transesterification Step Positive Regulation Of Telomere Maintenance ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity Phosphoglycolate Phosphatase Activity Positive Regulation Of Double-strand Break Repair Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Damage Response Regulation Of Protein Stability Positive Regulation Of Protein Localization To Nucleus Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity MRF Binding Response To Radiation Regulation Of Transcription By RNA Polymerase II Centriolar Satellite RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Purine Nucleotide Binding Double-stranded DNA Binding Positive Regulation Of Protein Localization To Nucleolus Regulation Of DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress Response To UV Metal Ion Binding Regulation Of Protein Localization To Nucleus Lens Fiber Cell Morphogenesis Poly(G) Binding Telomerase Inhibitor Activity G-quadruplex RNA Binding Regulation Of Mast Cell Chemotaxis	Keratin Filament Intermediate Filament Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Protein Binding Regulation Of RNA Metabolic Process
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