MRNIP and EFHC1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		MRNIP	EFHC1
Name		MRN complex interacting protein	EF-hand domain containing 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mre11 Complex	Spindle Pole Cytoplasm Centrosome Spindle Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Neuronal Cell Body Mitotic Spindle Axonemal A Tubule Inner Sheath
	Molecular Function	Chromatin Binding Protein Binding	Calcium Ion Binding Protein Binding Alpha-tubulin Binding
	Biological Process	DNA Repair DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Response To Ionizing Radiation Positive Regulation Of Protein Kinase Activity Protein Localization To Chromatin Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Flagellated Sperm Motility Regulation Of Cell Division Cilium-dependent Cell Motility
Diseases		None	Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		No GWAS studies recorded	Atopic march ( 26542096 ) Clozapine-induced myocarditis in schizophrenia ( 32066683 ) Mean platelet volume ( 27863252 ) Perceived intensity of glucose ( 31005972 ) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245 ) White blood cell count ( 32888494 )
Interacting Genes		9 interacting genes: DUSP23 EFHC1 EIF3E ENKD1 NUTF2 NXF1 PICK1 PKIA PSMB1	68 interacting genes: AKT1 CACNA1E CALCOCO2 CFAP161 CHCHD3 CIMIP1 DOK7 EFHC2 EIF4ENIF1 FMR1 GADD45B GAS2L2 GOLGA2 HOMER3 IHO1 IKZF3 IMP3 ITGB3BP KCNJ5-AS1 KCTD4 KRT15 KRT18 KRT75 LMO2 LRRC61 MAMDC2 MBD3L1 METTL27 MIIP MRNIP MTFR1L NQO2 NRIP3 NUP54 OIP5 PAX6 PBX1 PBX2 PMF1 PRR5L RCN1 REL RIMBP3 RNF125 SAPCD1 SELENOV SH3GLB2 SLAIN1 SNAI1 SORBS3 SPATA2 SYNGAP1 TCF4 TEKT1 TEX11 TLE5 TP53BP2 TRAF2 TRIP6 TRPM2 TSGA10IP TTC23L UBAP2 VBP1 WASF1 WHRN YJU2B ZBED1
Entrez ID		51149	114327
HPRD ID		17420	10583
Ensembl ID		ENSG00000161010	ENSG00000096093
Uniprot IDs		Q6NTE8	B2CKC5 Q5JVL4
PDB IDs		Not available	7UNG 8J07
GO Terms Enriched among Interactors		None	Protein Binding